Vector copy number (VCN) and Hb levels in long-term hematopoietic chimeras
| Group genotype . | n . | Months after transplantation . | VCN BM . | VCN blood . | Hb g/dL . | % Hbbhu . | Spleen mg . |
|---|---|---|---|---|---|---|---|
| GFP+/+ | 5 | 4-8 | NA | NA | 13.8 ± 1.0 | 0 | 108 ± 25 |
| GFP+/− | 5 | 4-8 | NA | NA | 8.1 ± 0.3 | 0 | 231 ± 58 |
| GFP−/− | 5 | 1.5-2 | NA | NA | 2.8 ± 0.8 | 0 | 800 ± 338 |
| TNS9−/− | 6 | 4-8 | 1.6 ± 0.6 | 1.2 ± 0.5 | 6.5 ± 2.9 | > 95 | 777 ± 382 |
| TNS9-1−/− | 1 | 4 | 1.7 | 1.6 | 5.7 | > 95 | 550 |
| TNS9-2−/− | 1 | 8 | 2.4 | 2.0 | 4.7 | > 97 | 1450 |
| TNS9-3−/− | 1 | 4 | 1.0 | 1.0 | 4.2 | > 97 | 829 |
| TNS9-4−/− | 1 | 5 | 0.9 | 1.0 | 5.0 | > 97 | 850 |
| TNS9-5−/− | 1 | 6 | 1.4 | 0.7 | 7.5 | > 97 | 650 |
| TNS9-6−/− | 1 | 6 | 2.2 | 1.1 | 12.0 | > 97 | 330 |
| Group genotype . | n . | Months after transplantation . | VCN BM . | VCN blood . | Hb g/dL . | % Hbbhu . | Spleen mg . |
|---|---|---|---|---|---|---|---|
| GFP+/+ | 5 | 4-8 | NA | NA | 13.8 ± 1.0 | 0 | 108 ± 25 |
| GFP+/− | 5 | 4-8 | NA | NA | 8.1 ± 0.3 | 0 | 231 ± 58 |
| GFP−/− | 5 | 1.5-2 | NA | NA | 2.8 ± 0.8 | 0 | 800 ± 338 |
| TNS9−/− | 6 | 4-8 | 1.6 ± 0.6 | 1.2 ± 0.5 | 6.5 ± 2.9 | > 95 | 777 ± 382 |
| TNS9-1−/− | 1 | 4 | 1.7 | 1.6 | 5.7 | > 95 | 550 |
| TNS9-2−/− | 1 | 8 | 2.4 | 2.0 | 4.7 | > 97 | 1450 |
| TNS9-3−/− | 1 | 4 | 1.0 | 1.0 | 4.2 | > 97 | 829 |
| TNS9-4−/− | 1 | 5 | 0.9 | 1.0 | 5.0 | > 97 | 850 |
| TNS9-5−/− | 1 | 6 | 1.4 | 0.7 | 7.5 | > 97 | 650 |
| TNS9-6−/− | 1 | 6 | 2.2 | 1.1 | 12.0 | > 97 | 330 |
NA indicates not applicable.