Table 1. Characteristics of ALCL and HD... | American Society of Hematology

Table 1.

Characteristics of ALCL and HD cell lines

Cell lines	Genetic lesions	Genotype	LD-PCR ofNPM/ALK	ALK protein expression
ALCL cell lines
Karpas 299	t(2;5)(p23;q35)	T cell	+(3.1 kb)	+
SU-DHL-1	t(2;5)(p23;q35)	T cell	+(2.1 kb)	+
DEL	t(5;6)(q35;p21)	B cell^*	+(1.4 kb)	+
SR-786	t(2;5)(p23;q35)	T cell	+(1.4 kb)	+
HD cell lines
KM-H2	Deletion in theIKBA gene	B cell	–	–
L428	Point mutation in the IKBA gene	B cell	–	–
HDLM-2	Not available	T cell	–	–

Cell lines	Genetic lesions	Genotype	LD-PCR ofNPM/ALK	ALK protein expression
ALCL cell lines
Karpas 299	t(2;5)(p23;q35)	T cell	+(3.1 kb)	+
SU-DHL-1	t(2;5)(p23;q35)	T cell	+(2.1 kb)	+
DEL	t(5;6)(q35;p21)	B cell^*	+(1.4 kb)	+
SR-786	t(2;5)(p23;q35)	T cell	+(1.4 kb)	+
HD cell lines
KM-H2	Deletion in theIKBA gene	B cell	–	–
L428	Point mutation in the IKBA gene	B cell	–	–
HDLM-2	Not available	T cell	–	–

Immunoglobulin heavy chain gene was rearranged.

+ indicates positive; –, negative.