Table 7. Maintenance of AML-CFC and AML... | American Society of Hematology

Table 7.

Maintenance of AML-CFC and AML LTC-IC numbers as AML cells exit G₀

Patient		No. of colonies per 10⁶input cells
Patient		Time 0	72 h, no GF	72 h + SF + FL + IL-3
1
	% G₀^7-150	99.8	34	0
	CFCs	ND	ND	ND
	LTC-ICs^7-151	241	640	447
2
	% G₀	98.0	6.6	7.2
	CFCs	800	NG	3750
	LTC-IC	3400	60 258	50 700
4
	% G₀	96.7	1.2	0.8
	CFCs	4700	51 500	29 000
	LTC-ICs	1406	74 400	59 733
5
	% G₀	96.1	1.1	0.6
	CFCs	ND	ND	ND
	LTC-ICs	10 220	32 941	9333

Patient		No. of colonies per 10⁶input cells
Patient		Time 0	72 h, no GF	72 h + SF + FL + IL-3
1
	% G₀^7-150	99.8	34	0
	CFCs	ND	ND	ND
	LTC-ICs^7-151	241	640	447
2
	% G₀	98.0	6.6	7.2
	CFCs	800	NG	3750
	LTC-IC	3400	60 258	50 700
4
	% G₀	96.7	1.2	0.8
	CFCs	4700	51 500	29 000
	LTC-ICs	1406	74 400	59 733
5
	% G₀	96.1	1.1	0.6
	CFCs	ND	ND	ND
	LTC-ICs	10 220	32 941	9333

ND indicates not done; and NG, no growth.

Percentage of G₀ cells in the population analyzed for CFC and LTC-IC content.

Number of LTC-derived colonies detected in methylcellulose assays of 5-week-old LTCs per 10⁶ cells initially plated in LTCs.