Table 5.

Multivariate analysis of death

VariablesRelative risk of death
(95% confidence interval)
P
HLA-identical sibling transplant versus
autologous transplant 
  
 First 6 mo after transplantation 1.93 (1.17-3.20) .01 
 Beyond 6 mo after transplantation 0.89 (0.47-1.68) .72 
Other significant variables   
 Karnofsky performance score at
transplantation 
  
  80% or less 1.00  
  90%-100% 0.62 (0.42-0.92) .02 
 Disease status at transplantation5-150   
  CR1 1.00  
  Second subsequent CR 1.66 (0.90-3.07) .10 
  Relapse 3.45 (2.06-5.78) < .0001  
  Primary induction failure 2.77 (1.62-4.74) .0002 
VariablesRelative risk of death
(95% confidence interval)
P
HLA-identical sibling transplant versus
autologous transplant 
  
 First 6 mo after transplantation 1.93 (1.17-3.20) .01 
 Beyond 6 mo after transplantation 0.89 (0.47-1.68) .72 
Other significant variables   
 Karnofsky performance score at
transplantation 
  
  80% or less 1.00  
  90%-100% 0.62 (0.42-0.92) .02 
 Disease status at transplantation5-150   
  CR1 1.00  
  Second subsequent CR 1.66 (0.90-3.07) .10 
  Relapse 3.45 (2.06-5.78) < .0001  
  Primary induction failure 2.77 (1.62-4.74) .0002 

CR indicates complete remission; and RR, relative risk.

F5-150

≥ Relapse 1 versus ≥ CR2, RR, 2.07 (95% CI, 1.17-3.67),P = .01; primary induction failure versus ≥ CR2, RR, 1.66 (95% CI, 0.92-3.02), P = .09; primary induction failure versus ≥ relapse 1, RR, 0.80 (95% CI, 0.49-1.30), P = .38.

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