Multivariate analysis of death
Variables . | Relative risk of death (95% confidence interval) . | P . |
---|---|---|
HLA-identical sibling transplant versus autologous transplant | ||
First 6 mo after transplantation | 1.93 (1.17-3.20) | .01 |
Beyond 6 mo after transplantation | 0.89 (0.47-1.68) | .72 |
Other significant variables | ||
Karnofsky performance score at transplantation | ||
80% or less | 1.00 | |
90%-100% | 0.62 (0.42-0.92) | .02 |
Disease status at transplantation5-150 | ||
CR1 | 1.00 | |
Second subsequent CR | 1.66 (0.90-3.07) | .10 |
Relapse | 3.45 (2.06-5.78) | < .0001 |
Primary induction failure | 2.77 (1.62-4.74) | .0002 |
Variables . | Relative risk of death (95% confidence interval) . | P . |
---|---|---|
HLA-identical sibling transplant versus autologous transplant | ||
First 6 mo after transplantation | 1.93 (1.17-3.20) | .01 |
Beyond 6 mo after transplantation | 0.89 (0.47-1.68) | .72 |
Other significant variables | ||
Karnofsky performance score at transplantation | ||
80% or less | 1.00 | |
90%-100% | 0.62 (0.42-0.92) | .02 |
Disease status at transplantation5-150 | ||
CR1 | 1.00 | |
Second subsequent CR | 1.66 (0.90-3.07) | .10 |
Relapse | 3.45 (2.06-5.78) | < .0001 |
Primary induction failure | 2.77 (1.62-4.74) | .0002 |
CR indicates complete remission; and RR, relative risk.
≥ Relapse 1 versus ≥ CR2, RR, 2.07 (95% CI, 1.17-3.67),P = .01; primary induction failure versus ≥ CR2, RR, 1.66 (95% CI, 0.92-3.02), P = .09; primary induction failure versus ≥ relapse 1, RR, 0.80 (95% CI, 0.49-1.30), P = .38.