Laboratory data at diagnosis of TL
Hematologic parameter at diagnosis . | Median . | Mean . | Range . |
|---|---|---|---|
| WBC count, × 109/L | 28.8 | 36.5 | 4.6-218.0 |
| Hemoglobin level, g/L | 14.6 | 14.2 | 6.9-21.6 |
| MCV, fL | 110 | 103 | 88-126 |
| Platelet count, × 109/L | 96 000 | 154 000 | 21 000-1 100 000 |
| Peripheral blasts, % | 25 | 29 | 0-87 |
| Bone marrow aspirate† | |||
| Bone marrow blasts, % | 23 | 26 | 0-87 |
| Peak values of bilirubin and hepatic enzymes during course of TL | |||
| Total bilirubin level, μM‡ | 180 | 170 | 12-617 |
| AST level, U/L§ | 70 | 190 | 23-1137 |
| ALT level, U/L§ | 45 | 144 | 8-1319 |
Hematologic parameter at diagnosis . | Median . | Mean . | Range . |
|---|---|---|---|
| WBC count, × 109/L | 28.8 | 36.5 | 4.6-218.0 |
| Hemoglobin level, g/L | 14.6 | 14.2 | 6.9-21.6 |
| MCV, fL | 110 | 103 | 88-126 |
| Platelet count, × 109/L | 96 000 | 154 000 | 21 000-1 100 000 |
| Peripheral blasts, % | 25 | 29 | 0-87 |
| Bone marrow aspirate† | |||
| Bone marrow blasts, % | 23 | 26 | 0-87 |
| Peak values of bilirubin and hepatic enzymes during course of TL | |||
| Total bilirubin level, μM‡ | 180 | 170 | 12-617 |
| AST level, U/L§ | 70 | 190 | 23-1137 |
| ALT level, U/L§ | 45 | 144 | 8-1319 |
WBC indicates white blood cell; MCV, mean corpuscular volume.
* n = 36.
n = 28; aspirates in 4 patients were nondiagnostic (consisting of 3 “dry taps” and one dilute specimen). Thus, for bone marrow blast percentage, n = 24.
n = 37; in 16 patients bilirubin was fractionated and was predominantly direct bilirubin.
n = 41.