Cytogenetics of neonatal TL as compared to recurrent leukemia
Patient . | TL . | Recurrent leukemia . |
|---|---|---|
| 1-AMKL | 47XX+21c[20] | 48XX+21c+21[11]; 47XY+21c[9] |
| 2-AMKL | 47XY+21cdel(16)(q21)[4]; 47XY+21c[16] | 47XY+21c[12] |
| 3-AMKL | 48XY+21c+11[4]; 47XY+21c[16] | 48XY+21c+11[8] |
| 4-AMKL | 47XY+21c[26]; 45-46XY+21c[4] (random loss) | 48XY+21c+8 |
| 5-ALL | 47XX+21c[20] | 47XX+21c[20] |
| 6-AMKL | 47XYqs,del(13)(q13q31)+21[20]/46XYqs[3] | 47XYqs,+21del(13)(q13q31), add(17)(p11.2)[12]/46XY[3] |
| 7-AMKL* | 47XY+21c[20] | 47XY+21c,isochrome 7(q10)[12] |
| 8-AMKL | 47XY+21c[20] | 49XY+21c+21+8[9]/47XY+21c[11] |
| 9-AMKL | 46XYder(14;21)(q10:q10)c+21c[5] | 46XY der(14;21)(q10:q10)c+21c[5]/46XYder(7)t(1;17)(q21;q36), der(14;21)(q10;q10)c+21c[5] |
Patient . | TL . | Recurrent leukemia . |
|---|---|---|
| 1-AMKL | 47XX+21c[20] | 48XX+21c+21[11]; 47XY+21c[9] |
| 2-AMKL | 47XY+21cdel(16)(q21)[4]; 47XY+21c[16] | 47XY+21c[12] |
| 3-AMKL | 48XY+21c+11[4]; 47XY+21c[16] | 48XY+21c+11[8] |
| 4-AMKL | 47XY+21c[26]; 45-46XY+21c[4] (random loss) | 48XY+21c+8 |
| 5-ALL | 47XX+21c[20] | 47XX+21c[20] |
| 6-AMKL | 47XYqs,del(13)(q13q31)+21[20]/46XYqs[3] | 47XYqs,+21del(13)(q13q31), add(17)(p11.2)[12]/46XY[3] |
| 7-AMKL* | 47XY+21c[20] | 47XY+21c,isochrome 7(q10)[12] |
| 8-AMKL | 47XY+21c[20] | 49XY+21c+21+8[9]/47XY+21c[11] |
| 9-AMKL | 46XYder(14;21)(q10:q10)c+21c[5] | 46XY der(14;21)(q10:q10)c+21c[5]/46XYder(7)t(1;17)(q21;q36), der(14;21)(q10;q10)c+21c[5] |
ALL indicates B-precursor acute lymphoblastic leukemia.
The one patient who died despite intensive therapy.