Differences between LSK+ and LSK-cells in proteins that are involved in the regulation of cell structure and motility
Accession no. . | Name . | Confidence . | Peptides found . | LSK-/LSK+ protein ratio . | LSK-/LSK+ mRNA ratio . | Gene symbol . |
|---|---|---|---|---|---|---|
| Q9CXK3 | Actin, alpha, cardiac | 99 | 168 | 1.563 | A | Actc1 |
| P63260 | Actin, gamma, cytoplasmic | 99 | 91 | 1.601 | 1.131 | Actg1 |
| P61161 | Actin-related protein (ARP) 2 | 99 | 19 | 1.204 | 1.099 | Actr2 |
| P59999 | ARP2/3 complex 20-kDa subunit | 99 | 15 | 1.242 | 1.295 | Arpc4 |
| Q9JM76 | ARP2/3 complex p21-Arc (subunit 3) | 99 | 9 | 1.261 | 2.572* | Arpc3 |
| Q9CVB6 | ARP2/3 complex, subunit 2 | 99 | 20 | 1.293 | 1.045 | Arpc2 |
| Q6UL10 | AHNAK | 99 | 29 | 2.151 | 4.530* | Ahnak |
| P07356 | Annexin A2 | 99 | 16 | 1.500 | 2.048* | Anxa2 |
| Q91ZU6 | Dystonin isoform a | 87 | 9 | 0.703 | 1.029 | Dst |
| Q9D952 | Envoplakin | 95 | 22 | 1.354 | A | Evpl |
| P26040 | Ezrin (cytovillin) (villin 2) | 99 | 25 | 1.294 | 1.064 | Vil2 |
| P13020 | Gelsolin (actin depolymerizing factor) | 99 | 9 | 2.122 | 2.490* | Gsn |
| Q920F2 | Keratin 5, type 2 | 99 | 7 | 1.608 | A | Krt2-5 |
| P04104 | Keratin, type 2 cytoskeletal 1 | 99 | 14 | 1.559 | A | Krt1 |
| Q6IFZ6 | Keratin complex 2, basic, gene 17 | 99 | 4 | 1.751 | A | Krt1b |
| P02535 | Keratin, type 1 cytoskeletal 10 | 99 | 4 | 2.911 | 1.276 | Krt10 |
| Q99N39 | Nadrin2 | 99 | 3 | 2.238 | 1.453 | Arhgap17 |
| Q80Y35 | Nuclear mitotic apparatus protein 1 | 99 | 17 | 0.654 | 0.859 | Numa1 |
| Q9QUI0 | RhoA | 99 | 16 | 1.288 | 2.001* | Rhoa |
| P20152 | Vimentin | 99 | 123 | 1.373 | 1.299* | Vim |
Accession no. . | Name . | Confidence . | Peptides found . | LSK-/LSK+ protein ratio . | LSK-/LSK+ mRNA ratio . | Gene symbol . |
|---|---|---|---|---|---|---|
| Q9CXK3 | Actin, alpha, cardiac | 99 | 168 | 1.563 | A | Actc1 |
| P63260 | Actin, gamma, cytoplasmic | 99 | 91 | 1.601 | 1.131 | Actg1 |
| P61161 | Actin-related protein (ARP) 2 | 99 | 19 | 1.204 | 1.099 | Actr2 |
| P59999 | ARP2/3 complex 20-kDa subunit | 99 | 15 | 1.242 | 1.295 | Arpc4 |
| Q9JM76 | ARP2/3 complex p21-Arc (subunit 3) | 99 | 9 | 1.261 | 2.572* | Arpc3 |
| Q9CVB6 | ARP2/3 complex, subunit 2 | 99 | 20 | 1.293 | 1.045 | Arpc2 |
| Q6UL10 | AHNAK | 99 | 29 | 2.151 | 4.530* | Ahnak |
| P07356 | Annexin A2 | 99 | 16 | 1.500 | 2.048* | Anxa2 |
| Q91ZU6 | Dystonin isoform a | 87 | 9 | 0.703 | 1.029 | Dst |
| Q9D952 | Envoplakin | 95 | 22 | 1.354 | A | Evpl |
| P26040 | Ezrin (cytovillin) (villin 2) | 99 | 25 | 1.294 | 1.064 | Vil2 |
| P13020 | Gelsolin (actin depolymerizing factor) | 99 | 9 | 2.122 | 2.490* | Gsn |
| Q920F2 | Keratin 5, type 2 | 99 | 7 | 1.608 | A | Krt2-5 |
| P04104 | Keratin, type 2 cytoskeletal 1 | 99 | 14 | 1.559 | A | Krt1 |
| Q6IFZ6 | Keratin complex 2, basic, gene 17 | 99 | 4 | 1.751 | A | Krt1b |
| P02535 | Keratin, type 1 cytoskeletal 10 | 99 | 4 | 2.911 | 1.276 | Krt10 |
| Q99N39 | Nadrin2 | 99 | 3 | 2.238 | 1.453 | Arhgap17 |
| Q80Y35 | Nuclear mitotic apparatus protein 1 | 99 | 17 | 0.654 | 0.859 | Numa1 |
| Q9QUI0 | RhoA | 99 | 16 | 1.288 | 2.001* | Rhoa |
| P20152 | Vimentin | 99 | 123 | 1.373 | 1.299* | Vim |
Protein accession numbers refer to SWISS-PROT or TrEMBL entries. For explanation of confidence and peptides found, see Table 2. All proteins are significantly different (P > .05) between LSK+ cells and LSK- cells.
A indicates this mRNA was called “absent” in the microarray experiments.
Significantly different mRNA ratios (P < .05).