Table 3. Summary of antileukemic... | American Society of Hematology

Table 3.

Summary of antileukemic properties for IFN subtypes

IFN subtype	A1	A2	A4	A5	A6	A9	B
Antiproliferative	+	+	+	+	+	++	+
Differentiation	−	+	++	+	+	−	−
Decreased viability	++	+	++	++	++	+	+
Apoptosis	−	−	−	=	−	++	−
Delayed onset of erythroleukemia	++	+	+	+	++	++	−
Increased survival rate from erythroleukemia	+	−	+	+	++	++	−

IFN subtype	A1	A2	A4	A5	A6	A9	B
Antiproliferative	+	+	+	+	+	++	+
Differentiation	−	+	++	+	+	−	−
Decreased viability	++	+	++	++	++	+	+
Apoptosis	−	−	−	=	−	++	−
Delayed onset of erythroleukemia	++	+	+	+	++	++	−
Increased survival rate from erythroleukemia	+	−	+	+	++	++	−

++ indicates significant increase; +, increase; −, no change; and =, significant decrease.