Phosphotyrosine peptides common to Bcr-Abl–containing cells
PSDB ID . | NCBI access no. . | pTyr site . | Peptide . | Bcr-Abl link . | Present in U937 . | Present in EoL-1 . |
|---|---|---|---|---|---|---|
| Abl | NP_005148 | 185 | INTASDGKLyVSSESR | + | - | - |
| Abl | NP_005148 | 226 | NKPTVyGVSPNYDK | + | - | - |
| Abl | NP_005148 | 393 | LMTGDTyTAHAGAK | + | - | - |
| Bcr | NP_004318 | 177 | GHGQPGADAEKPFyVNVEFHHER | + | - | - |
| Cbl | NP_005179 | 674 | IKPSSSANAlySLAAR | + | - | + |
| CD2AP | NP_036252 | 548 | DTCYSPKPSVyLSTPSSASK | - | - | - |
| cdc2 | NP_001777 | 15 | IEKIGEGTyGWYK | - | + | + |
| cdk3 | NP_001249 | 15 | VEKIGEGTyGWYK | - | + | - |
| DYRK1A | NP_001387 | 321 | IYQylQSR | - | + | + |
| GRF1 | NP_004482 | 1106 | NEEENlySVPHDSTQGK | - | - | - |
| GSK3-β | NP_002084 | 216 | GEPNVSylCSR | - | + | + |
| HIPK1 | NP_689909 | 352 | AVCSTyLQSR | - | + | - |
| SHIP-2 | NP_001558 | 986 | NSFNNPAyYVLEGVPHQLLPPEPPSPAR | + | - | + |
| SHIP-2 | NP_001558 | 1135 | TLSEVDyAPAGPAR | + | - | - |
| Erk1 | NP_002737 | 204 | IADPEHDHTGFLTEyVATR | + | + | + |
| Erk2 | NP_002736 | 187 | VADPDHDHTGFLTEyVATR | + | + | + |
| PRP4 | NP_003904 | 849 | LCDFGSASHVADNDITPyLVSR | - | + | + |
| Shc | NP_892113 | 427 | ELFDDPSyVNVQNLDKAR | + | - | + |
| VASP | NP_001008736 | 39 | VQlyHNPTANSFR | + | - | - |
PSDB ID . | NCBI access no. . | pTyr site . | Peptide . | Bcr-Abl link . | Present in U937 . | Present in EoL-1 . |
|---|---|---|---|---|---|---|
| Abl | NP_005148 | 185 | INTASDGKLyVSSESR | + | - | - |
| Abl | NP_005148 | 226 | NKPTVyGVSPNYDK | + | - | - |
| Abl | NP_005148 | 393 | LMTGDTyTAHAGAK | + | - | - |
| Bcr | NP_004318 | 177 | GHGQPGADAEKPFyVNVEFHHER | + | - | - |
| Cbl | NP_005179 | 674 | IKPSSSANAlySLAAR | + | - | + |
| CD2AP | NP_036252 | 548 | DTCYSPKPSVyLSTPSSASK | - | - | - |
| cdc2 | NP_001777 | 15 | IEKIGEGTyGWYK | - | + | + |
| cdk3 | NP_001249 | 15 | VEKIGEGTyGWYK | - | + | - |
| DYRK1A | NP_001387 | 321 | IYQylQSR | - | + | + |
| GRF1 | NP_004482 | 1106 | NEEENlySVPHDSTQGK | - | - | - |
| GSK3-β | NP_002084 | 216 | GEPNVSylCSR | - | + | + |
| HIPK1 | NP_689909 | 352 | AVCSTyLQSR | - | + | - |
| SHIP-2 | NP_001558 | 986 | NSFNNPAyYVLEGVPHQLLPPEPPSPAR | + | - | + |
| SHIP-2 | NP_001558 | 1135 | TLSEVDyAPAGPAR | + | - | - |
| Erk1 | NP_002737 | 204 | IADPEHDHTGFLTEyVATR | + | + | + |
| Erk2 | NP_002736 | 187 | VADPDHDHTGFLTEyVATR | + | + | + |
| PRP4 | NP_003904 | 849 | LCDFGSASHVADNDITPyLVSR | - | + | + |
| Shc | NP_892113 | 427 | ELFDDPSyVNVQNLDKAR | + | - | + |
| VASP | NP_001008736 | 39 | VQlyHNPTANSFR | + | - | - |
Bcr-Abl-containing cell lines were BV173, K562, KCL22, KU812, SD1, and SUP-B15. Control cell line was U937. Peptides found in the U937 and EoL-1 cells are indicated.