p53 and EBV status of BL cell lines and primary lymphomas
. | Origin . | EBV status . | p53 . | Snk/PIk2 methylation . |
|---|---|---|---|---|
| BL cell line | ||||
| Akata | Japanese | Positive | Codon 190 CTT del.1 | Yes |
| BJAB | African | Negative | Codon 193 CAT>CgT (His→Arg) | Yes |
| BL2 | Caucasian | Negative | Wild-type | Yes |
| BL30 | Caucasian | Negative | Codon 246 ATg>ACg (Met→Thr) | Yes |
| BL37 | Caucasian | Positive | Codon 237 ATg>ATA (Met→Ileu) | Yes |
| BL40 | Caucasian | Negative | Wild-type | Yes |
| BL41 | Caucasian | Negative | Codon 248 Cgg>CAg (Arg→Gln) | Yes |
| DG75 | Unknown | Negative | Codon 283 CgC>CAC (Arg→His) | Yes |
| Louckes | American | Negative | Codon 238 TgT>TAT (Cys→Tyr) | Yes |
| Mutu 111 | African | Positive | Codon 245 ggC>gAC (Gly→Asp) | Yes |
| Namalwa | African | Positive | Codon 248 Cgg>CAg (Arg→Gln) | Yes |
| P3HR1 | African | Positive | Codon 287 gAg>TAg (Glu→Stop) | Yes |
| Rael | African | Positive | Codon 184 gAT>AAT (Asp→Asn) | Yes |
| Raji | African | Positive | Codon 213 CgA>CAA (Arg→Gln) | Yes |
| Ramos | American | Negative | Codon 254 ATC>gAC (Ile→Asp) | Yes |
| Primary BL | ||||
| 1 | African | Positive | Wild-type | Yes |
| 2 | African | Positive | Wild-type | Yes |
| 3 | African | Positive | Codon 175 CgC>CAC (Arg→His) | Yes |
| 4 | African | Positive | Wild-type | Yes |
| 5 | African | Positive | Codon 248 Cgg>Tgg (Arg→Trp) | Yes |
| 6 | African | Positive | Wild-type | Yes |
| 7 | African | Positive | Codon 175 CgC>CAC (Arg→His) | Yes |
| 8 | African | Positive | Wild-type | Yes |
| 9 | African | Positive | Wild-type | No |
| 10 | African | Positive | Wild-type | Yes |
. | Origin . | EBV status . | p53 . | Snk/PIk2 methylation . |
|---|---|---|---|---|
| BL cell line | ||||
| Akata | Japanese | Positive | Codon 190 CTT del.1 | Yes |
| BJAB | African | Negative | Codon 193 CAT>CgT (His→Arg) | Yes |
| BL2 | Caucasian | Negative | Wild-type | Yes |
| BL30 | Caucasian | Negative | Codon 246 ATg>ACg (Met→Thr) | Yes |
| BL37 | Caucasian | Positive | Codon 237 ATg>ATA (Met→Ileu) | Yes |
| BL40 | Caucasian | Negative | Wild-type | Yes |
| BL41 | Caucasian | Negative | Codon 248 Cgg>CAg (Arg→Gln) | Yes |
| DG75 | Unknown | Negative | Codon 283 CgC>CAC (Arg→His) | Yes |
| Louckes | American | Negative | Codon 238 TgT>TAT (Cys→Tyr) | Yes |
| Mutu 111 | African | Positive | Codon 245 ggC>gAC (Gly→Asp) | Yes |
| Namalwa | African | Positive | Codon 248 Cgg>CAg (Arg→Gln) | Yes |
| P3HR1 | African | Positive | Codon 287 gAg>TAg (Glu→Stop) | Yes |
| Rael | African | Positive | Codon 184 gAT>AAT (Asp→Asn) | Yes |
| Raji | African | Positive | Codon 213 CgA>CAA (Arg→Gln) | Yes |
| Ramos | American | Negative | Codon 254 ATC>gAC (Ile→Asp) | Yes |
| Primary BL | ||||
| 1 | African | Positive | Wild-type | Yes |
| 2 | African | Positive | Wild-type | Yes |
| 3 | African | Positive | Codon 175 CgC>CAC (Arg→His) | Yes |
| 4 | African | Positive | Wild-type | Yes |
| 5 | African | Positive | Codon 248 Cgg>Tgg (Arg→Trp) | Yes |
| 6 | African | Positive | Wild-type | Yes |
| 7 | African | Positive | Codon 175 CgC>CAC (Arg→His) | Yes |
| 8 | African | Positive | Wild-type | Yes |
| 9 | African | Positive | Wild-type | No |
| 10 | African | Positive | Wild-type | Yes |
p53 status of BL lines was obtained from published sources21-23 or established by direct sequence analysis as described in “Materials and methods.”