Table 1.

Characteristics of MCL cell lines




Checkpoint alterations
MCL cell line
LD 50, nM
p53
ATM
p16
JVM-2   18.2 ± 1.3   wt   wt   wt  
GRANTA-519   19.4 ± 1.8   wt   mut   del  
JEKO   26.6 ± 2.2   mut   wt   wt  
REC-1
 
60.1 ± 1.6
 
wt
 
wt
 
del
 



Checkpoint alterations
MCL cell line
LD 50, nM
p53
ATM
p16
JVM-2   18.2 ± 1.3   wt   wt   wt  
GRANTA-519   19.4 ± 1.8   wt   mut   del  
JEKO   26.6 ± 2.2   mut   wt   wt  
REC-1
 
60.1 ± 1.6
 
wt
 
wt
 
del
 

wt indicates wild type; mut, mutated; and del, deletion.

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