Factors associated with disease relapse and OS in ALL (univariate and multivariate analysis)
. | Relapse . | . | . | . | Overall survival . | . | . | . | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| . | Univariate . | Multivariate . | . | . | Univariate . | Multivariate . | . | . | ||||||
| Variable . | P . | Odds ratio . | 95% CI . | P . | P . | Odds ratio . | 95% CI . | P . | ||||||
| Patient older than 30 y | .086 | 1.2 | 0.53-2.96 | NS | .028 | 1.5 | 0.74-3.04 | NS | ||||||
| Transplantation in relapse | < .001 | 8.2 | 2.51-27.3 | .001 | .016 | 2.8 | 1.10-7.59 | .030 | ||||||
| Female patient | .047 | 0.49 | 0.21-1.12 | NS | NS | – | – | – | ||||||
| Patient CMV positive | NS | – | – | – | .068 | 1.2 | 0.60-2.57 | NS | ||||||
| Donor older than 30 y | NS | – | – | – | .072 | 1.5 | 0.75-3.25 | NS | ||||||
| DPB1 mismatch | .013 | 0.31 | 0.15-0.64 | .002 | .025 | 0.58 | 0.31-1.07 | .084 | ||||||
. | Relapse . | . | . | . | Overall survival . | . | . | . | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| . | Univariate . | Multivariate . | . | . | Univariate . | Multivariate . | . | . | ||||||
| Variable . | P . | Odds ratio . | 95% CI . | P . | P . | Odds ratio . | 95% CI . | P . | ||||||
| Patient older than 30 y | .086 | 1.2 | 0.53-2.96 | NS | .028 | 1.5 | 0.74-3.04 | NS | ||||||
| Transplantation in relapse | < .001 | 8.2 | 2.51-27.3 | .001 | .016 | 2.8 | 1.10-7.59 | .030 | ||||||
| Female patient | .047 | 0.49 | 0.21-1.12 | NS | NS | – | – | – | ||||||
| Patient CMV positive | NS | – | – | – | .068 | 1.2 | 0.60-2.57 | NS | ||||||
| Donor older than 30 y | NS | – | – | – | .072 | 1.5 | 0.75-3.25 | NS | ||||||
| DPB1 mismatch | .013 | 0.31 | 0.15-0.64 | .002 | .025 | 0.58 | 0.31-1.07 | .084 | ||||||