Table 4.

Characteristics according to type of chronic GVHD




De novo

Relapsing

Progressive

P
No. patients   17   30   16   —  
Response (CR/PR), no. (%)   13 (76)   17 (57)   7 (44)   .07  
More than 2 prior treatments, no. (%)*  3 (18)   13 (48)   7 (44)   .05  
Platelet count below 100 000/mm3 at ECP, no. (%)  5 (29)   8 (27)   11 (69)   .3  
Scleroderma, no. (%)  11/14 (79)§  9/27 (33)   1/9 (11)   .002  
Time from chronic GVHD to ECP, median (range)
 
512 (23-1537)
 
263 (1-1205)
 
90 (4-1351)
 
.02
 



De novo

Relapsing

Progressive

P
No. patients   17   30   16   —  
Response (CR/PR), no. (%)   13 (76)   17 (57)   7 (44)   .07  
More than 2 prior treatments, no. (%)*  3 (18)   13 (48)   7 (44)   .05  
Platelet count below 100 000/mm3 at ECP, no. (%)  5 (29)   8 (27)   11 (69)   .3  
Scleroderma, no. (%)  11/14 (79)§  9/27 (33)   1/9 (11)   .002  
Time from chronic GVHD to ECP, median (range)
 
512 (23-1537)
 
263 (1-1205)
 
90 (4-1351)
 
.02
 

— indicates not applicable.

*

Including tacrolimus or cyclosporine.

100 000/mm3 is equal to 100 × 109/L.

When skin was the only organ involved.

§

Eleven out of 14 patients with scleroderma.

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