Table 5.

Factors affecting nonrelapse mortality in patients without de novo chronic GVHD




No.

HR

95% CI

P
Response to ECP*     
    CR/PR   23   0.3   0.1-0.8   .01  
    All others   21   —   —   —  
Platelets at ECP     
    Fewer than 100,000/mm3  19   29   6.2-142   < .001  
    100,000/mm3 or more   25   —   —   —  
LDH     
    1000 IU/L or lower   30   —   —   —  
    More than 1000 IU/L   15   3.1   1.4-6.9   .005  
No. prior treatments     
    2   25   2.4   0.9-6.1   .06  
    3
 
20
 

 

 

 



No.

HR

95% CI

P
Response to ECP*     
    CR/PR   23   0.3   0.1-0.8   .01  
    All others   21   —   —   —  
Platelets at ECP     
    Fewer than 100,000/mm3  19   29   6.2-142   < .001  
    100,000/mm3 or more   25   —   —   —  
LDH     
    1000 IU/L or lower   30   —   —   —  
    More than 1000 IU/L   15   3.1   1.4-6.9   .005  
No. prior treatments     
    2   25   2.4   0.9-6.1   .06  
    3
 
20
 

 

 

 

— indicates not applicable.

*

Including tacrolimus or cyclosporine.

100 000/mm3 is equal to 100 × 109/L.

Evaluated since time of response. Two patients who died on the day the response was evaluated are excluded.

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