Table 2.

Hematologic and coagulation parameters




Adamts13+/+

Adamts13-/-
Haptoglobin, %   100 ± 67   103 ± 69  
VWF antigen, %   100 ± 23   129 ± 31* 
FVIII activity, %   100 ± 10   146 ± 22 
Fibrinogen, %   100 ± 5   98 ± 7  
PT, s   16.1 ± 0.8   16.0 ± 1.0  
APTT, s   44.2 ± 3.7   43.3 ± 2.5  
Blood loss, μL
 
12.5 ± 8.4
 
9.5 ± 3.1
 



Adamts13+/+

Adamts13-/-
Haptoglobin, %   100 ± 67   103 ± 69  
VWF antigen, %   100 ± 23   129 ± 31* 
FVIII activity, %   100 ± 10   146 ± 22 
Fibrinogen, %   100 ± 5   98 ± 7  
PT, s   16.1 ± 0.8   16.0 ± 1.0  
APTT, s   44.2 ± 3.7   43.3 ± 2.5  
Blood loss, μL
 
12.5 ± 8.4
 
9.5 ± 3.1
 

Values are mean ± SD of 12 mice in each genotype except for the blood loss, where it is mean ± SD of 18 mice.

*

P < .05 when compared with Adamts13+/+ mice

P < .001 when compared with Adamts 13+/+ mice.

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