Distribution of HLA DR and DQ alleles in patients with and without inhibitors
. | No. patients (no. patients with severe hemophilia A) . | . | |
|---|---|---|---|
| Allele . | Inhibitor patients . | Noninhibitor patients . | |
| HLA DR | |||
| *01 | 9 (8) | 16 (11) | |
| *03 | 26 (22) | 20 (15) | |
| *04 | 20 (12) | 28 (19) | |
| *07 | 21 (18) | 21 (14) | |
| *08 | 7 (7) | 4 (4) | |
| *10 | 2 (1) | 6 (3) | |
| *11 | 20 (16) | 18 (10) | |
| *12 | 0 (0) | 1 (0) | |
| *13 | 18 (15) | 21 (13) | |
| *14 | 5 (4) | 5 (4) | |
| *15 | 21 (18) | 29 (25) | |
| *16 | 5 (5) | 5 (4) | |
| Total | 154 (126) | 174 (122) | |
| HLA DQ | |||
| *02 | 35 (31) | 32 (23) | |
| *03 | 53 (39) | 57 (35) | |
| *04 | 3 (3) | 5 (5) | |
| *0501 | 13 (11) | 18 (11) | |
| *0502 | 7 (7) | 5 (4) | |
| *0503 | 4 (3) | 5 (4) | |
| *0601 | 5 (5) | 5 (5) | |
| *0602 | 17 (14) | 25 (21) | |
| *0603 | 8 (6) | 10 (5) | |
| *0604 | 5 (3) | 6 (4) | |
| *0609 | 0 (0) | 1 (0) | |
| *0619 | 0 (0) | 1 (1) | |
| Total | 150 (122) | 170 (118) | |
. | No. patients (no. patients with severe hemophilia A) . | . | |
|---|---|---|---|
| Allele . | Inhibitor patients . | Noninhibitor patients . | |
| HLA DR | |||
| *01 | 9 (8) | 16 (11) | |
| *03 | 26 (22) | 20 (15) | |
| *04 | 20 (12) | 28 (19) | |
| *07 | 21 (18) | 21 (14) | |
| *08 | 7 (7) | 4 (4) | |
| *10 | 2 (1) | 6 (3) | |
| *11 | 20 (16) | 18 (10) | |
| *12 | 0 (0) | 1 (0) | |
| *13 | 18 (15) | 21 (13) | |
| *14 | 5 (4) | 5 (4) | |
| *15 | 21 (18) | 29 (25) | |
| *16 | 5 (5) | 5 (4) | |
| Total | 154 (126) | 174 (122) | |
| HLA DQ | |||
| *02 | 35 (31) | 32 (23) | |
| *03 | 53 (39) | 57 (35) | |
| *04 | 3 (3) | 5 (5) | |
| *0501 | 13 (11) | 18 (11) | |
| *0502 | 7 (7) | 5 (4) | |
| *0503 | 4 (3) | 5 (4) | |
| *0601 | 5 (5) | 5 (5) | |
| *0602 | 17 (14) | 25 (21) | |
| *0603 | 8 (6) | 10 (5) | |
| *0604 | 5 (3) | 6 (4) | |
| *0609 | 0 (0) | 1 (0) | |
| *0619 | 0 (0) | 1 (1) | |
| Total | 150 (122) | 170 (118) | |
Numbers of patients with severe hemophilia A are shown in parentheses.