Frequencies of allele 134 bp in the IL10G microsatellite
. | No. with severe hemophilia A . | . | No. with moderate Hemophilia A . | . | No. with mild hemophilia A . | . | . | |||
|---|---|---|---|---|---|---|---|---|---|---|
| IL10G . | Inhibitor positive . | Inhibitor negative . | Inhibitor positive . | Inhibitor negative . | Inhibitor positive . | Inhibitor negative . | Total (%) . | |||
| Allele 134 positive | 26 | 7 | 3 | 3 | 3 | 2 | 44 (26.8) | |||
| Allele 134 negative | 37 | 54 | 4 | 16 | 4 | 5 | 120 (73.2) | |||
| Total | 63* | 61 | 7 | 19 | 7 | 7 | 164 (100) | |||
. | No. with severe hemophilia A . | . | No. with moderate Hemophilia A . | . | No. with mild hemophilia A . | . | . | |||
|---|---|---|---|---|---|---|---|---|---|---|
| IL10G . | Inhibitor positive . | Inhibitor negative . | Inhibitor positive . | Inhibitor negative . | Inhibitor positive . | Inhibitor negative . | Total (%) . | |||
| Allele 134 positive | 26 | 7 | 3 | 3 | 3 | 2 | 44 (26.8) | |||
| Allele 134 negative | 37 | 54 | 4 | 16 | 4 | 5 | 120 (73.2) | |||
| Total | 63* | 61 | 7 | 19 | 7 | 7 | 164 (100) | |||
OR, 5.4 (95% CI, 2.1-13.7; P < .001) for the presence of allele 134 among patients with severe hemophilia A and inhibitors.