Cooperation between p50 and p52 is essential for the development of lymph nodes
Genotype . | No. . | Inguinal . | Brachial . | Axillary . | Facial . | Cervical . | Periaortic . | Mesenteric . |
|---|---|---|---|---|---|---|---|---|
| WT | 6 | 12/12 | 12/12 | 12/12 | 12/12 | 12/12 | 18/18 | 18/18 |
| Nfkb1+/–Nfkb2+/– | 6 | 12/12 | 12/12 | 12/12 | 12/12 | 12/12 | 18/18 | 18/18 |
| Nfkb1–/– | 10 | 4/20 | 20/20 | 20/20 | 20/20 | 20/20 | 29/30 | 30/30 |
| Nfkb2–/– | 9 | 4/18 | 18/18 | 18/18 | 18/18 | 18/18 | 26/27 | 27/27 |
| Nfkb1–/–Nfkb2+/– | 5 | 0/10 | 1/10 | 8/10 | 8/10 | 4/10 | 14/15 | 15/15 |
| Nfkb1+/–Nfkb2–/– | 9 | 0/18 | 0/18 | 0/18 | 1/18 | 0/18 | 1/27 | 16/27 |
| Nfkb1–/–Nfkb2–/– | 6 | 0/12 | 0/12 | 0/12 | 0/12 | 0/12 | 0/18 | 0/18 |
Genotype . | No. . | Inguinal . | Brachial . | Axillary . | Facial . | Cervical . | Periaortic . | Mesenteric . |
|---|---|---|---|---|---|---|---|---|
| WT | 6 | 12/12 | 12/12 | 12/12 | 12/12 | 12/12 | 18/18 | 18/18 |
| Nfkb1+/–Nfkb2+/– | 6 | 12/12 | 12/12 | 12/12 | 12/12 | 12/12 | 18/18 | 18/18 |
| Nfkb1–/– | 10 | 4/20 | 20/20 | 20/20 | 20/20 | 20/20 | 29/30 | 30/30 |
| Nfkb2–/– | 9 | 4/18 | 18/18 | 18/18 | 18/18 | 18/18 | 26/27 | 27/27 |
| Nfkb1–/–Nfkb2+/– | 5 | 0/10 | 1/10 | 8/10 | 8/10 | 4/10 | 14/15 | 15/15 |
| Nfkb1+/–Nfkb2–/– | 9 | 0/18 | 0/18 | 0/18 | 1/18 | 0/18 | 1/27 | 16/27 |
| Nfkb1–/–Nfkb2–/– | 6 | 0/12 | 0/12 | 0/12 | 0/12 | 0/12 | 0/18 | 0/18 |
Denominators denote the normal number of lymph nodes of each type counted and found in a wild-type mouse.