Characteristics of patients with or without FLT3/ITD
. | FLT3/ITD . | ITD vs WT, P . | FLT3/WT . | ALM vs WT, P . | FLT3/ALM . |
|---|---|---|---|---|---|
| No. patients | 77 | 515 | 38 | ||
| Median age, y (range) | 12.6 (0.6-19.8) | < .001 | 10.0 (0.01-20.9) | .625 | 11.0 (0.3-19.7) |
| Age below 1 y, no. (%) | 1 (1.3) | .013 | 49 (9.5) | .966 | 3 (7.9) |
| Sex, no. (%) | |||||
| Male | 42 (54.5) | .973 | 276 (53.6) | .230 | 16 (42.1) |
| Female | 35 (45.5) | 239 (46.4) | 22 (57.9) | ||
| Race, no. (%) | |||||
| White | 58 (76.3) | .076 | 331 (65.3) | .586 | 27 (71.1) |
| Nonwhite | 18 (23.7) | 176 (34.7) | 11 (28.9) | ||
| Unknown | 1 | 8 | 0 | ||
| Median WBC count, × 109/L (range) | 71.9 (1.8-860) | < .001 | 19.1 (0.3-684) | .744 | 19.85 (1.0-267.3) |
| Marrow blast, % (range) | 85 (24-100) | < .001 | 67 (0-100) | .004 | 83.5 (29-100) |
| FAB class, no. (%) | |||||
| M0 | 4 (5.2) | .764 | 22 (4.3) | .243 | 3 (7.9) |
| M1 | 25 (32.5) | < .001 | 75 (14.6) | .089 | 10 (26.3) |
| M2 | 24 (31.2) | .769 | 148 (28.8) | .403 | 8 (21.1) |
| M4 | 16 (20.8) | .289 | 140 (27.2) | .319 | 7 (18.4) |
| M5 | 7 (9.1) | .105 | 88 (17.1) | .421 | 9 (23.7) |
| M6 | 1 (1.3) | .999 | 12 (2.3) | .999 | 0 (0) |
| M7 | 0 (0) | .148 | 17 (3.3) | .999 | 1 (2.6) |
| Unknown | 0 | 13 | 0 |
. | FLT3/ITD . | ITD vs WT, P . | FLT3/WT . | ALM vs WT, P . | FLT3/ALM . |
|---|---|---|---|---|---|
| No. patients | 77 | 515 | 38 | ||
| Median age, y (range) | 12.6 (0.6-19.8) | < .001 | 10.0 (0.01-20.9) | .625 | 11.0 (0.3-19.7) |
| Age below 1 y, no. (%) | 1 (1.3) | .013 | 49 (9.5) | .966 | 3 (7.9) |
| Sex, no. (%) | |||||
| Male | 42 (54.5) | .973 | 276 (53.6) | .230 | 16 (42.1) |
| Female | 35 (45.5) | 239 (46.4) | 22 (57.9) | ||
| Race, no. (%) | |||||
| White | 58 (76.3) | .076 | 331 (65.3) | .586 | 27 (71.1) |
| Nonwhite | 18 (23.7) | 176 (34.7) | 11 (28.9) | ||
| Unknown | 1 | 8 | 0 | ||
| Median WBC count, × 109/L (range) | 71.9 (1.8-860) | < .001 | 19.1 (0.3-684) | .744 | 19.85 (1.0-267.3) |
| Marrow blast, % (range) | 85 (24-100) | < .001 | 67 (0-100) | .004 | 83.5 (29-100) |
| FAB class, no. (%) | |||||
| M0 | 4 (5.2) | .764 | 22 (4.3) | .243 | 3 (7.9) |
| M1 | 25 (32.5) | < .001 | 75 (14.6) | .089 | 10 (26.3) |
| M2 | 24 (31.2) | .769 | 148 (28.8) | .403 | 8 (21.1) |
| M4 | 16 (20.8) | .289 | 140 (27.2) | .319 | 7 (18.4) |
| M5 | 7 (9.1) | .105 | 88 (17.1) | .421 | 9 (23.7) |
| M6 | 1 (1.3) | .999 | 12 (2.3) | .999 | 0 (0) |
| M7 | 0 (0) | .148 | 17 (3.3) | .999 | 1 (2.6) |
| Unknown | 0 | 13 | 0 |