Cox regression analysis of prognostic factors for progression-free survival from study entry
. | Univariate . | . | . | . | Multivariate . | . | ||||
|---|---|---|---|---|---|---|---|---|---|---|
| . | Yes . | No . | . | . | . | . | ||||
| Variable . | No. patients (%) . | . | HR (95% CI) . | P . | HR (95% CI) . | P . | ||||
| FLT3/ITD-high AR | 54 (9) | 576 (91) | 2.6 (1.8-3.6) | < .001 | 2.6 (1.6-4.4) | < .001 | ||||
| High-risk cytogenetics | 16 (4) | 366 (96) | 2.6 (1.1-5.9) | .023 | 2.4 (1.1-5.6) | .034 | ||||
| WBC count over 100 × 109/L | 104 (7) | 526 (83) | 1.7 (1.2-2.3) | .002 | 1.5 (1.0-2.2) | .073 | ||||
| African American | 60 (10) | 561 (90) | 1.3 (0.9-2.0) | .144 | 1.7 (1.0-2.7) | .031 | ||||
. | Univariate . | . | . | . | Multivariate . | . | ||||
|---|---|---|---|---|---|---|---|---|---|---|
| . | Yes . | No . | . | . | . | . | ||||
| Variable . | No. patients (%) . | . | HR (95% CI) . | P . | HR (95% CI) . | P . | ||||
| FLT3/ITD-high AR | 54 (9) | 576 (91) | 2.6 (1.8-3.6) | < .001 | 2.6 (1.6-4.4) | < .001 | ||||
| High-risk cytogenetics | 16 (4) | 366 (96) | 2.6 (1.1-5.9) | .023 | 2.4 (1.1-5.6) | .034 | ||||
| WBC count over 100 × 109/L | 104 (7) | 526 (83) | 1.7 (1.2-2.3) | .002 | 1.5 (1.0-2.2) | .073 | ||||
| African American | 60 (10) | 561 (90) | 1.3 (0.9-2.0) | .144 | 1.7 (1.0-2.7) | .031 | ||||
For the univariate analysis, n = 630; for the multivariate analysis, n = 375.