Table 1.

Modified Rai stages or lymphadenopathy/splenomegaly or β2-microglobulin and ZAP-70 percentages



Rai stage

Lymphadenopathy/splenomegaly*

β2-microglobulin*

Low
Int/high*
Present
Absent
Greater than 2.2 mg/mL
Less than 2.2 mg/mL
Total, no. (%)   87 (30)   202 (70)   101 (35)   188 (65)   121 (46)   144 (54)  
ZAP-70, no. (%)       
    Greater than 20%   12 (12)   92 (88)   66 (63)   38 (37)   56 (46)   31 (22)  
    Lower than 20%
 
75 (41)
 
110 (59)
 
35 (19)
 
150 (81)
 
65 (54)
 
113 (78)
 


Rai stage

Lymphadenopathy/splenomegaly*

β2-microglobulin*

Low
Int/high*
Present
Absent
Greater than 2.2 mg/mL
Less than 2.2 mg/mL
Total, no. (%)   87 (30)   202 (70)   101 (35)   188 (65)   121 (46)   144 (54)  
ZAP-70, no. (%)       
    Greater than 20%   12 (12)   92 (88)   66 (63)   38 (37)   56 (46)   31 (22)  
    Lower than 20%
 
75 (41)
 
110 (59)
 
35 (19)
 
150 (81)
 
65 (54)
 
113 (78)
 

For ZAP-70 greater than 20%, n = 104 (36%); for ZAP-70 lower than 20%, n = 185 (64%)

n indicates the number of samples.

*

As determined by the 2-tailed Fisher exact test.

P < .001

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