Table 2.

Mortality rate, disability at 3 to 6 months and at 1 year or more




Acute death, no. (%)

Total death, no. (%)

Outcome at 3 to 6 mo, no. patients

Outcome at 1 y or more, no. patients
Study, year
No. of patients
Tot
Death
Level of disability
Tot
Death
Level of disability
Appenzeller et al,28  2005   24   0 (0)   0 (0)   NA   NA   NA   24   0   Complete recovery: 13; neurologic impairment: 11  
Stolz et al,9,10  2005   79   12 (15.2)   14 (17.7)   62   0   mRS 0-1: 54; mRS 2-3: 4; mRS 4-5: 4   58   2   mRS 0-1: 50; mRS 2-3: 2; mRS 4-5: 4  
Ferro et al,1,27  2005   624   27 (4.3)   52 (8.3)   589   15   mRS 0-1: 481; mRS 2: 49; mRS 3-5: 44   582   10   mRS 0-1: 493; mRS 2: 47; mRS 3-5: 32  
Favrole et al,11  2004   28   0 (0)   0 (0)   28   0   mRS 0-1: 26; mRS 2: 1; mRS 4: 1   NA   NA   NA  
Baumgartner et al,12  2003   33   0 (0)   0 (0)   NA   NA   NA   33   0   mRS 0-2: 27; mRS > 2: 6  
Buccino et al,13  2003   36   NA   1 (2.8)   NA   NA   NA   35   1   mRS 0-1: 34  
Cakmak et al,14  2003   16   0 (0)   0 (0)   16   0   mRS 0-1: 9; mRS 2: 5; mRS 3-5: 2   NA   NA   NA  
Breteau et al,21  2003   55   4 (7.3)   7 (12.7)   NA   NA   NA   51   3   mRS 0-2: 45; mRS 3-5: 3  
Ferro et al,16  2002   142   9 (6.3)   11 (7.7)   NA   NA   NA   126   2   mRS 0-1: 108; mRS 2: 12; mRS 3-5: 4  
Strupp et al,17  2002   40   NA   NA   NA   NA   NA   40   NA   Complete or partial recovery: 29; focal neurologic deficits: 11  
Fink and McAuley,18  2001   25   NA   1 (4)   NA   NA   NA   25   1   mRS 0-1: 16; mRS 2: 7; mRS > 3: 1  
de Bruijn et al,4,19  2001   59   6 (10.2)   8 (13.6)   53   0   mRS 0-2: 49; mRS > 3: 4   49   2   mRS 0-1: 25; mRS 2-3: 19; mRS > 3: 3  
Lleo et al,23  1999   17   0 (0)   2 (11.8)   17   2   mRS 0-2: 10; mRS 3-5: 5   NA   NA   NA  
Preter et al,24  1996   85   6 (7.1)   8 (9.4)   79   2   NA   77   0   mRS 0-1: 66; optic atrophy: 2; seizure alone: 4; neuropsychiatric disturbance: 3; hemispheric deficit: 1; multiple cn palsies, cerebellar incoordination: 1  
Rondepierre et al,25  1995   18   2 (11.1)   7 (39)   16   5   GOS 1-2: 10; GOS 3-5: 1   NA   NA   NA  
Bienfait et al,26  1995
 
62
 
NA
 
11 (17.7)
 
62
 
11
 
mRS 0-2: 41; mRS 3-5: 10
 
NA
 
NA
 
NA
 



Acute death, no. (%)

Total death, no. (%)

Outcome at 3 to 6 mo, no. patients

Outcome at 1 y or more, no. patients
Study, year
No. of patients
Tot
Death
Level of disability
Tot
Death
Level of disability
Appenzeller et al,28  2005   24   0 (0)   0 (0)   NA   NA   NA   24   0   Complete recovery: 13; neurologic impairment: 11  
Stolz et al,9,10  2005   79   12 (15.2)   14 (17.7)   62   0   mRS 0-1: 54; mRS 2-3: 4; mRS 4-5: 4   58   2   mRS 0-1: 50; mRS 2-3: 2; mRS 4-5: 4  
Ferro et al,1,27  2005   624   27 (4.3)   52 (8.3)   589   15   mRS 0-1: 481; mRS 2: 49; mRS 3-5: 44   582   10   mRS 0-1: 493; mRS 2: 47; mRS 3-5: 32  
Favrole et al,11  2004   28   0 (0)   0 (0)   28   0   mRS 0-1: 26; mRS 2: 1; mRS 4: 1   NA   NA   NA  
Baumgartner et al,12  2003   33   0 (0)   0 (0)   NA   NA   NA   33   0   mRS 0-2: 27; mRS > 2: 6  
Buccino et al,13  2003   36   NA   1 (2.8)   NA   NA   NA   35   1   mRS 0-1: 34  
Cakmak et al,14  2003   16   0 (0)   0 (0)   16   0   mRS 0-1: 9; mRS 2: 5; mRS 3-5: 2   NA   NA   NA  
Breteau et al,21  2003   55   4 (7.3)   7 (12.7)   NA   NA   NA   51   3   mRS 0-2: 45; mRS 3-5: 3  
Ferro et al,16  2002   142   9 (6.3)   11 (7.7)   NA   NA   NA   126   2   mRS 0-1: 108; mRS 2: 12; mRS 3-5: 4  
Strupp et al,17  2002   40   NA   NA   NA   NA   NA   40   NA   Complete or partial recovery: 29; focal neurologic deficits: 11  
Fink and McAuley,18  2001   25   NA   1 (4)   NA   NA   NA   25   1   mRS 0-1: 16; mRS 2: 7; mRS > 3: 1  
de Bruijn et al,4,19  2001   59   6 (10.2)   8 (13.6)   53   0   mRS 0-2: 49; mRS > 3: 4   49   2   mRS 0-1: 25; mRS 2-3: 19; mRS > 3: 3  
Lleo et al,23  1999   17   0 (0)   2 (11.8)   17   2   mRS 0-2: 10; mRS 3-5: 5   NA   NA   NA  
Preter et al,24  1996   85   6 (7.1)   8 (9.4)   79   2   NA   77   0   mRS 0-1: 66; optic atrophy: 2; seizure alone: 4; neuropsychiatric disturbance: 3; hemispheric deficit: 1; multiple cn palsies, cerebellar incoordination: 1  
Rondepierre et al,25  1995   18   2 (11.1)   7 (39)   16   5   GOS 1-2: 10; GOS 3-5: 1   NA   NA   NA  
Bienfait et al,26  1995
 
62
 
NA
 
11 (17.7)
 
62
 
11
 
mRS 0-2: 41; mRS 3-5: 10
 
NA
 
NA
 
NA
 

mRS indicates modified Rankin Score; GOS, Glasgow Outcome Scale; NA, not assessed; Tot, total number of evaluable patients at each follow-up visit; Death, total number of patient deaths at each follow-up visit; and Level of disability, number of patients with different levels of disability.

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