Table 7.

Outcome of 361 patients older than 60 with AML according to cytogenetic risk group and age


AMLSG score

No. of patients

CR, %

Median OS, mo

3-y OS (95% CI)
Younger than 70 y     
    Not high risk   161   62   17.5   0.26 (0.20-0.33)  
    High risk   82   21   7.2   0.06 (0.02-0.13)  
70 y or older     
    Not high risk   72   39   6.3   0.06 (0.02-0.13)  
    High risk
 
46
 
15
 
3.1
 
0.02 (0.00-0.10)
 

AMLSG score

No. of patients

CR, %

Median OS, mo

3-y OS (95% CI)
Younger than 70 y     
    Not high risk   161   62   17.5   0.26 (0.20-0.33)  
    High risk   82   21   7.2   0.06 (0.02-0.13)  
70 y or older     
    Not high risk   72   39   6.3   0.06 (0.02-0.13)  
    High risk
 
46
 
15
 
3.1
 
0.02 (0.00-0.10)
 

Cytogenetic risk stratification according to the system proposed in this study.

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