Baseline characteristics of the patients
Characteristic . | Patients without G6PD deficiency . | Patients with G6PD deficiency . | Female with partial G6PD deficiency* . |
---|---|---|---|
No. of patients | 82 | 26 | 4 |
Age, y | 44.48 ± 10.34 | 45.40 ± 9.66 | 45.55 ± 12.62 |
Male, no. (%) | 73 (89) | 20 (77) | 0 (0) |
Weight, kg | 71.29 ± 10.45 | 69.93 ± 11.83 | 55.35 ± 4.73 |
Body mass index† | 24.95 ± 2.77 | 24.88 ± 3.14 | 23.50 ± 2.65 |
Mean corpuscular volume, μm3 | 83.54 ± 9.28 | 87.05 ± 7.54 | 95.75 ± 0.25 |
Hemoglobin, g/dL‡ | 14.37 ± 1.18 | 13.32 ± 1.06 | 13.50 ± 0.94 |
Bilirubin, mg/dL | 0.60 ± 0.27 | 0.76 ± 0.43 | 1.10 ± 0.51 |
Ribavirin administered/body weight, mg/kg | 13.75 ± 1.15 | 13.52 ± 1.19 | 14.53 ± 1.21 |
Alanine aminotransferase, U/L§ | 132.90 ± 93.20 | 151.90 ± 117.60 | 119.50 ± 44.74 |
Mean HCV RNA level, IU/mL × 106 | 0.72 ± 0.48 | 0.67 ± 0.87 | 0.91 ± 0.70 |
HCV genotype, no. (%) | |||
1 | 34 (41) | 13 (50) | 2 (50) |
2 | 9 (11) | 4 (15) | 0 (0) |
3 | 22 (27) | 7 (27) | 1 (25) |
4 | 17 (21) | 2 (8) | 1 (25) |
Characteristic . | Patients without G6PD deficiency . | Patients with G6PD deficiency . | Female with partial G6PD deficiency* . |
---|---|---|---|
No. of patients | 82 | 26 | 4 |
Age, y | 44.48 ± 10.34 | 45.40 ± 9.66 | 45.55 ± 12.62 |
Male, no. (%) | 73 (89) | 20 (77) | 0 (0) |
Weight, kg | 71.29 ± 10.45 | 69.93 ± 11.83 | 55.35 ± 4.73 |
Body mass index† | 24.95 ± 2.77 | 24.88 ± 3.14 | 23.50 ± 2.65 |
Mean corpuscular volume, μm3 | 83.54 ± 9.28 | 87.05 ± 7.54 | 95.75 ± 0.25 |
Hemoglobin, g/dL‡ | 14.37 ± 1.18 | 13.32 ± 1.06 | 13.50 ± 0.94 |
Bilirubin, mg/dL | 0.60 ± 0.27 | 0.76 ± 0.43 | 1.10 ± 0.51 |
Ribavirin administered/body weight, mg/kg | 13.75 ± 1.15 | 13.52 ± 1.19 | 14.53 ± 1.21 |
Alanine aminotransferase, U/L§ | 132.90 ± 93.20 | 151.90 ± 117.60 | 119.50 ± 44.74 |
Mean HCV RNA level, IU/mL × 106 | 0.72 ± 0.48 | 0.67 ± 0.87 | 0.91 ± 0.70 |
HCV genotype, no. (%) | |||
1 | 34 (41) | 13 (50) | 2 (50) |
2 | 9 (11) | 4 (15) | 0 (0) |
3 | 22 (27) | 7 (27) | 1 (25) |
4 | 17 (21) | 2 (8) | 1 (25) |
Data are expressed as means ± SD. Conversion to SI units for bilirubin: mg/dL × 17.1 = μM.
Patients with partial G6PD deficiency were not included in the statistical analysis because of their small number
The body mass index is the weight in kilograms divided by square of the height in meters
P < .001 for the comparison between patients with and without G6PD deficiency, by Mann-Whitney test
Normal value, ≤ 41 U/L