Table 3.

Absolute annual incidence of first venous thromboembolism and arterial cardiovascular disease




Follow-up years, no.

Individuals with event, no.

Absolute incidence/y, % (95% CI)

Hazard ratio (95% CI)
VTE     
   Wild type   806   1   0.12 (0.00-0.69)   
   Carrier   810   3   0.37 (0.08-1.08)   3.1 (0.3-29.7)  
Idiopathic VTE     
   Wild type   806   1   0.12 (0.00-0.69)   
   Carrier   810   2   0.24 (0.03-0.89)   2.1 (0.2-22.6)  
Any arterial cardiovascular event     
   Wild type   828   6   0.73 (0.27-1.58)   
   Carrier   888   5   0.56 (0.18-1.31)   0.8 (0.2-2.6)  
Myocardial infarction     
   Wild type   867   3   0.35 (0.07-1.01)   
   Carrier   917   3   0.33 (0.07-0.96)   0.9 (0.2-4.6)  
Ischemic stroke/transient ischemic attack     
   Wild type   863   2   0.23 (0.03-0.84)   
   Carrier   918   3   0.33 (0.07-0.96)   1.4 (0.2-8.5)  
Other arterial events     
   Wild type   832   2   0.24 (0.03-0.87)   
   Carrier
 
896
 
0
 
0.00 (0.00-0.41)
 

 



Follow-up years, no.

Individuals with event, no.

Absolute incidence/y, % (95% CI)

Hazard ratio (95% CI)
VTE     
   Wild type   806   1   0.12 (0.00-0.69)   
   Carrier   810   3   0.37 (0.08-1.08)   3.1 (0.3-29.7)  
Idiopathic VTE     
   Wild type   806   1   0.12 (0.00-0.69)   
   Carrier   810   2   0.24 (0.03-0.89)   2.1 (0.2-22.6)  
Any arterial cardiovascular event     
   Wild type   828   6   0.73 (0.27-1.58)   
   Carrier   888   5   0.56 (0.18-1.31)   0.8 (0.2-2.6)  
Myocardial infarction     
   Wild type   867   3   0.35 (0.07-1.01)   
   Carrier   917   3   0.33 (0.07-0.96)   0.9 (0.2-4.6)  
Ischemic stroke/transient ischemic attack     
   Wild type   863   2   0.23 (0.03-0.84)   
   Carrier   918   3   0.33 (0.07-0.96)   1.4 (0.2-8.5)  
Other arterial events     
   Wild type   832   2   0.24 (0.03-0.87)   
   Carrier
 
896
 
0
 
0.00 (0.00-0.41)
 

 

— indicates no hazard ratio calculated due to absence of events in carrier group

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