Activation of the proximal promoter of LMO2 in LMO2-rearranged T-ALL patients
. | Total LMO2 mRNA . | . | Long LMO2 mRNA . | . | . | . | ||
|---|---|---|---|---|---|---|---|---|
| Patient ID, by mutation . | dCt . | Expression level . | dCt . | Expression level . | Long transcripts, % . | Proximal transcripts, % . | ||
| Del(11)(p12p13) | ||||||||
| 1950 | 6.14 | 0.58577 | 8.52 | 0.05421 | 9.3 | 90.7 | ||
| 2846 | 7.24 | 0.19499 | 10.15 | 0.01062 | 5.4 | 94.6 | ||
| LMO2 translocation | ||||||||
| 2789 | 6.81 | 0.29974 | 9.11 | 0.03005 | 10.0 | 90.0 | ||
| 2735 | 6.96 | 0.25799 | 9.43 | 0.02182 | 8.5 | 91.5 | ||
. | Total LMO2 mRNA . | . | Long LMO2 mRNA . | . | . | . | ||
|---|---|---|---|---|---|---|---|---|
| Patient ID, by mutation . | dCt . | Expression level . | dCt . | Expression level . | Long transcripts, % . | Proximal transcripts, % . | ||
| Del(11)(p12p13) | ||||||||
| 1950 | 6.14 | 0.58577 | 8.52 | 0.05421 | 9.3 | 90.7 | ||
| 2846 | 7.24 | 0.19499 | 10.15 | 0.01062 | 5.4 | 94.6 | ||
| LMO2 translocation | ||||||||
| 2789 | 6.81 | 0.29974 | 9.11 | 0.03005 | 10.0 | 90.0 | ||
| 2735 | 6.96 | 0.25799 | 9.43 | 0.02182 | 8.5 | 91.5 | ||
dCt indicates the expression of indicated promoter transcripts relative to the housekeeping gene GAPDH