Table 2.

Log-rank statistics to test the equality of the survival distributions for the different categoric variables in 39 cases of gastric DLBCL and DLCLML


Variable

n

P
Translocation vs no translocation cases   15 vs 24   .333  
Ig/BCL6 vs non-Ig/BCL6 translocation cases   10 vs 5   .360  
Deregulating mutation vs no deregulating mutation cases   8 vs 31   .784  
Translocation/deregulating mutation vs no translocation/deregulating mutation cases   22 vs 17   .315  
Ongoing BCL6 somatic mutations in MMC [GCB] vs acquired but not active ongoing BCL6 somatic mutations in MMC [post-GCB] cases   6 vs 16   .734  
High BCL6 expression vs low BCL6 expression cases*
 
26 vs 12
 
.016
 

Variable

n

P
Translocation vs no translocation cases   15 vs 24   .333  
Ig/BCL6 vs non-Ig/BCL6 translocation cases   10 vs 5   .360  
Deregulating mutation vs no deregulating mutation cases   8 vs 31   .784  
Translocation/deregulating mutation vs no translocation/deregulating mutation cases   22 vs 17   .315  
Ongoing BCL6 somatic mutations in MMC [GCB] vs acquired but not active ongoing BCL6 somatic mutations in MMC [post-GCB] cases   6 vs 16   .734  
High BCL6 expression vs low BCL6 expression cases*
 
26 vs 12
 
.016
 

MMC indicates major mutation cluster located at 5′ of the first intron.

*

BCL6 protein expression was assessed by a 4-point system based on the proportion of positive cells with nuclear staining and was scored as low (- and +) or high (++ and +++). BCL6 expression could not be studied in 1 case due to the unavailability of paraffin block for the case.

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