Summary of clinical responses according to FLT3 mutation status
. | Patients, no. (%) . | . | . | . | |||
|---|---|---|---|---|---|---|---|
| Response . | All patients . | Patients not receiving hydroxyurea . | FLT3 mutant patients . | FLT3 wild-type patients . | |||
| Complete remission | 0 (0) | 0 (0) | 0 (0) | 0 (0) | |||
| Partial remission | 0 (0) | 0 (0) | 0 (0) | 0 (0) | |||
| Bone marrow response | 5 (19) | 5 (22) | 0 (0) | 5 (23) | |||
| Hematologic response | 3 (11) | 1 (4) | 3 (60) | 0 (0) | |||
| No response | 14 (52) | 13 (57) | 1 (20) | 13 (59) | |||
| Progressive disease | 5 (19) | 4 (17) | 1 (20) | 4 (18) | |||
. | Patients, no. (%) . | . | . | . | |||
|---|---|---|---|---|---|---|---|
| Response . | All patients . | Patients not receiving hydroxyurea . | FLT3 mutant patients . | FLT3 wild-type patients . | |||
| Complete remission | 0 (0) | 0 (0) | 0 (0) | 0 (0) | |||
| Partial remission | 0 (0) | 0 (0) | 0 (0) | 0 (0) | |||
| Bone marrow response | 5 (19) | 5 (22) | 0 (0) | 5 (23) | |||
| Hematologic response | 3 (11) | 1 (4) | 3 (60) | 0 (0) | |||
| No response | 14 (52) | 13 (57) | 1 (20) | 13 (59) | |||
| Progressive disease | 5 (19) | 4 (17) | 1 (20) | 4 (18) | |||
Total number of patients was 27; 23 of whom did not receive hydroxyurea. There were 5 FLT3 mutant patients and 22 FLT3 wild-type patients.