Bone marrow differentials between WT and Siat1Δ P1 mice
. | WT . | Siat1ΔP1 . | P* . |
|---|---|---|---|
| Total myeloid cells, % | |||
| Proliferative | 10.0 ± 1.8 | 13.8 ± 0.6 | < .005 |
| Myeloblasts | 0.9 | 1.4 | |
| Promyeloblasts | 3.0 | 4.8 | |
| Myelocytes | 6.2 | 7.5 | |
| Nonproliferative | 55.1 ± 5.4 | 55.5 ± 1.9 | .90 |
| Metamyelocytes | 11.5 | 12.9 | |
| Band neutrophils | 19.4 | 19.1 | |
| Segmented neutrophils | 24.3 | 23.5 | |
| Total monocytes, % | 0.86 ± 0.70 | 1.52 ± 0.61 | .21 |
| Total lymphocytes, % | 17.2 ± 5.8 | 14.2 ± 2.3 | .32 |
| Total erythroid cells, % | |||
| Proliferative | 6.2 ± 1.3 | 5.6 ± 0.8 | .43 |
| Rubriblasts | 0.8 | 1.2 | |
| Prorubricytes | 1.6 | 1.6 | |
| Rubricytes | 3.8 | 2.8 | |
| Nonproliferative | 10.6 ± 2.1 | 9.5 ± 4.5 | .47 |
| Metarubricytes | 10.6 | 9.5 | |
| Myeloid-erythroid ratio | 3.97 ± 0.72 | 4.66 ± 0.60 | .19 |
| Myeloid proliferative-nonproliferative ratio | 0.18 ± 0.04 | 0.25 ± 0.01 | < .01 |
| Erythroid proliferative-nonproliferative ratio | 0.59 ± 0.15 | 0.64 ± 0.18 | .73 |
. | WT . | Siat1ΔP1 . | P* . |
|---|---|---|---|
| Total myeloid cells, % | |||
| Proliferative | 10.0 ± 1.8 | 13.8 ± 0.6 | < .005 |
| Myeloblasts | 0.9 | 1.4 | |
| Promyeloblasts | 3.0 | 4.8 | |
| Myelocytes | 6.2 | 7.5 | |
| Nonproliferative | 55.1 ± 5.4 | 55.5 ± 1.9 | .90 |
| Metamyelocytes | 11.5 | 12.9 | |
| Band neutrophils | 19.4 | 19.1 | |
| Segmented neutrophils | 24.3 | 23.5 | |
| Total monocytes, % | 0.86 ± 0.70 | 1.52 ± 0.61 | .21 |
| Total lymphocytes, % | 17.2 ± 5.8 | 14.2 ± 2.3 | .32 |
| Total erythroid cells, % | |||
| Proliferative | 6.2 ± 1.3 | 5.6 ± 0.8 | .43 |
| Rubriblasts | 0.8 | 1.2 | |
| Prorubricytes | 1.6 | 1.6 | |
| Rubricytes | 3.8 | 2.8 | |
| Nonproliferative | 10.6 ± 2.1 | 9.5 ± 4.5 | .47 |
| Metarubricytes | 10.6 | 9.5 | |
| Myeloid-erythroid ratio | 3.97 ± 0.72 | 4.66 ± 0.60 | .19 |
| Myeloid proliferative-nonproliferative ratio | 0.18 ± 0.04 | 0.25 ± 0.01 | < .01 |
| Erythroid proliferative-nonproliferative ratio | 0.59 ± 0.15 | 0.64 ± 0.18 | .73 |
Female mice between 55 and 65 days of age were analyzed. Differentials were based on 500 cell counts. Total values are expressed as percentages of total population and, where shown, ± SD. Additional cells, including plasma cells and binucleated cells, consisted of less than 0.5%. Cells not included in the counts were the occasional macrophages, mitotic figures, and megakaryocytes.
Difference between WT and Siat1Δ P1.