Table 1.

Patient characteristics


Patient no.

Prior Tx

Rai stage

ZAP-70

IgVh status

Cytogenetics

WBC, × 109/L

Endogenous dGTP, μM
1   T   2   +   -   ND   45   3.8  
2   UNT   1   -   ND   46,XX{20}   159   4.4  
3   UNT   3   -   ND   46,XY{11]   114   3.7  
4   UNT   3   +   -   47,XX,+12[4]/46,XX[11]   280   2.5  
5   UNT   4   -   +   46,XY {20}   360   0.3  
6   UNT   0   ND   ND   46,XY,del{13} {q12q14} {7}/46,XY{13}   43   0.9  
7   UNT   1   ND   ND   Random numeral and structural changes {2}/46,XY{18}   78   0.9  
8   UNT   1   +   -   46,XY {20}   52   0.8  
9   UNT   1   ND   ND   46,XX{12}   243   3.1  
10   UNT   2   -   +   46,XX {20}   127   2.7  
11   UNT   1   +   ND   ND   35   ND  
12
 
T
 
3
 
-
 
ND
 
46,XY {15}
 
228
 
1.0
 

Patient no.

Prior Tx

Rai stage

ZAP-70

IgVh status

Cytogenetics

WBC, × 109/L

Endogenous dGTP, μM
1   T   2   +   -   ND   45   3.8  
2   UNT   1   -   ND   46,XX{20}   159   4.4  
3   UNT   3   -   ND   46,XY{11]   114   3.7  
4   UNT   3   +   -   47,XX,+12[4]/46,XX[11]   280   2.5  
5   UNT   4   -   +   46,XY {20}   360   0.3  
6   UNT   0   ND   ND   46,XY,del{13} {q12q14} {7}/46,XY{13}   43   0.9  
7   UNT   1   ND   ND   Random numeral and structural changes {2}/46,XY{18}   78   0.9  
8   UNT   1   +   -   46,XY {20}   52   0.8  
9   UNT   1   ND   ND   46,XX{12}   243   3.1  
10   UNT   2   -   +   46,XX {20}   127   2.7  
11   UNT   1   +   ND   ND   35   ND  
12
 
T
 
3
 
-
 
ND
 
46,XY {15}
 
228
 
1.0
 

Tx indicates therapy; T, Treated; UNT, untreated; and ND, not done.

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