Table 4. Odds ratios and 95% CIs for... | American Society of Hematology

Table 4.

Odds ratios and 95% CIs for adverse health status among HCT survivors by cGVHD and treatment characteristics

	General health			Mental health			Functional impairment			Activity limitations			Pain			Anxiety			Any domain
	OR	95% CI	OR	95% CI	OR	95% CI	OR	95% CI	OR	95% CI	OR	95% CI	OR	95% CI
cGHVD
None	1.0	—	1.0	—	1.0	—	1.0	—	1.0	—	1.0	—	1.0	—
Resolved	1.0	0.5-1.5	1.0	0.6-1.6	1.2	0.7-2.1	1.1	0.6-1.8	1.1	0.6-2.0	0.6	0.3-1.1	0.9	0.6-1.4
Active	2.7^*	1.6-4.6^*	2.7^*	1.6-4.4^*	5.6^*	3.3-9.4^*	5.1^*	3.1-8.3^*	4.2^*	2.4-7.1^*	1.5	0.8-2.6	5.1^*	2.8-7.9^*
Sex
Female	0.7	0.4-1.1	1.0	0.7-1.5	1.7^*	1.1-2.7^*	1.6	1.0-2.4	1.0	0.6-1.5	1.4	0.9-2.4	1.3	0.9-1.9
Male	1.0	—	1.0	—	1.0	—	1.0	—	1.0	—	1.0	—	1.0	—
Age at interview
18-45 y	1.0	—	1.0	—	1.0	—	1.0	—	1.0	—	1.0	—	1.0	—
Older than 45 y	1.2	0.8-1.9	0.9	0.6-1.4	1.7^*	1.1-2.7^*	1.2	0.8-1.8	0.8	0.5-1.2	1.0	0.6-1.7	1.3	0.9-2.0
Time since transplantation
2-5 y	1.9^*	1.1-3.3^*	1.3	0.7-2.1	1.4	0.8-2.5	1.7	1.0-2.9	1.5	0.8-2.8	2.2^*	1.1-4.4^*	1.8^*	1.1-2.7^*
6-10 y	1.3	0.7-2.3	1.3	0.8-2.3	1.3	0.7-2.4	1.0	0.6-1.7	1.5	0.9-3.9	2.2^*	1.1-4.4^*	1.4	0.9-2.2
11-28 y	1.0	—	1.0	—	1.0	—	1.0	—	1.0	—	1.0	—	1.0	—
Donor type
Related	1.0	—	1.0	—	1.0	—	1.0	—	1.0	—	1.0	—	1.0	—
Unrelated	1.3	0.7-2.2	0.9	0.5-1.5	2.3^*	1.3-3.9^*	1.3	0.8-2.2	1.2	0.7-2.1	0.8	0.4-1.6	1.2	0.7-1.9
Conditioning regimen
Chemotherapy	1.0	—	1.0	—	1.0	—	1.0	—	1.0	—	1.0	—	1.0	—
Radiation and chemotherapy	1.4	0.6-3.2	1.3	0.6-2.8	0.6	0.3-1.3	2.9^*	1.2-7.4^*	1.5	0.6-3.5	0.9	0.4-2.1	1.2	0.6-2.1

	General health			Mental health			Functional impairment			Activity limitations			Pain			Anxiety			Any domain
	OR	95% CI	OR	95% CI	OR	95% CI	OR	95% CI	OR	95% CI	OR	95% CI	OR	95% CI
cGHVD
None	1.0	—	1.0	—	1.0	—	1.0	—	1.0	—	1.0	—	1.0	—
Resolved	1.0	0.5-1.5	1.0	0.6-1.6	1.2	0.7-2.1	1.1	0.6-1.8	1.1	0.6-2.0	0.6	0.3-1.1	0.9	0.6-1.4
Active	2.7^*	1.6-4.6^*	2.7^*	1.6-4.4^*	5.6^*	3.3-9.4^*	5.1^*	3.1-8.3^*	4.2^*	2.4-7.1^*	1.5	0.8-2.6	5.1^*	2.8-7.9^*
Sex
Female	0.7	0.4-1.1	1.0	0.7-1.5	1.7^*	1.1-2.7^*	1.6	1.0-2.4	1.0	0.6-1.5	1.4	0.9-2.4	1.3	0.9-1.9
Male	1.0	—	1.0	—	1.0	—	1.0	—	1.0	—	1.0	—	1.0	—
Age at interview
18-45 y	1.0	—	1.0	—	1.0	—	1.0	—	1.0	—	1.0	—	1.0	—
Older than 45 y	1.2	0.8-1.9	0.9	0.6-1.4	1.7^*	1.1-2.7^*	1.2	0.8-1.8	0.8	0.5-1.2	1.0	0.6-1.7	1.3	0.9-2.0
Time since transplantation
2-5 y	1.9^*	1.1-3.3^*	1.3	0.7-2.1	1.4	0.8-2.5	1.7	1.0-2.9	1.5	0.8-2.8	2.2^*	1.1-4.4^*	1.8^*	1.1-2.7^*
6-10 y	1.3	0.7-2.3	1.3	0.8-2.3	1.3	0.7-2.4	1.0	0.6-1.7	1.5	0.9-3.9	2.2^*	1.1-4.4^*	1.4	0.9-2.2
11-28 y	1.0	—	1.0	—	1.0	—	1.0	—	1.0	—	1.0	—	1.0	—
Donor type
Related	1.0	—	1.0	—	1.0	—	1.0	—	1.0	—	1.0	—	1.0	—
Unrelated	1.3	0.7-2.2	0.9	0.5-1.5	2.3^*	1.3-3.9^*	1.3	0.8-2.2	1.2	0.7-2.1	0.8	0.4-1.6	1.2	0.7-1.9
Conditioning regimen
Chemotherapy	1.0	—	1.0	—	1.0	—	1.0	—	1.0	—	1.0	—	1.0	—
Radiation and chemotherapy	1.4	0.6-3.2	1.3	0.6-2.8	0.6	0.3-1.3	2.9^*	1.2-7.4^*	1.5	0.6-3.5	0.9	0.4-2.1	1.2	0.6-2.1

Odds significantly higher compared to reference group (indicated by dashes)