Table 1. Increases of mean fluorescence... | American Society of Hematology

Table 1.

Increases of mean fluorescence intensity reflecting surface expression level of α_IIbβ₃ and CD42b by K562 cells after treatment by PHA/PMA/act D- or PHA/act D-generated MVs

	PHA + PMA + act D			PHA + act D
	β_IIbβ₃	CD42b	α_IIbβ₃	CD42b
Control cells	53.3 ± 4.6	63.4 ± 8.9	33.2 ± 1.7	55.7 ± 9.6
MV
1 μg/mL	403.8 ± 40.2*	81.4 ± 26.7	ND	ND
5 μg/mL	493.3 ± 58.3†	113.6 ± 9.2*	56.7 ± 7.8	78.9 ± 22.3
10 μg/mL	680.2 ± 62.5†	286.7 ± 45.2*	78.9 ± 8.4*	106.4 ± 22.9*

	PHA + PMA + act D			PHA + act D
	β_IIbβ₃	CD42b	α_IIbβ₃	CD42b
Control cells	53.3 ± 4.6	63.4 ± 8.9	33.2 ± 1.7	55.7 ± 9.6
MV
1 μg/mL	403.8 ± 40.2*	81.4 ± 26.7	ND	ND
5 μg/mL	493.3 ± 58.3†	113.6 ± 9.2*	56.7 ± 7.8	78.9 ± 22.3
10 μg/mL	680.2 ± 62.5†	286.7 ± 45.2*	78.9 ± 8.4*	106.4 ± 22.9*

Results are expressed as ± SEM. Data are from 8 experiments.

ND indicates not determined.

P < .05 significantly different from control cells.

†

P < .01, significantly different from control cells.

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