Short-term radioprotection by limiting injection of fetal liver cells
. | No. of mice that survived until week 4 after transplantation . | . | |
---|---|---|---|
No. of cells injected/mouse . | CXCR4+/+ . | CXCR4-/- . | |
5 × 106 | 5/5 | 5/5 | |
2 × 106 | 5/5 | 2/5 | |
106 | 4/5 | 1/5 | |
0.5 × 106 | 2/5 | 0/5 | |
0.25 × 106 | 2/5 | 0/5 |
. | No. of mice that survived until week 4 after transplantation . | . | |
---|---|---|---|
No. of cells injected/mouse . | CXCR4+/+ . | CXCR4-/- . | |
5 × 106 | 5/5 | 5/5 | |
2 × 106 | 5/5 | 2/5 | |
106 | 4/5 | 1/5 | |
0.5 × 106 | 2/5 | 0/5 | |
0.25 × 106 | 2/5 | 0/5 |
Freshly isolated fetal liver cells were engrafted to lethally irradiated recipient mice by limiting injection of cells as indicated. All values are expressed as “n/5,” meaning the number of mice who survived (n) when 5 mice were engrafted.