Table 1.

Short-term radioprotection by limiting injection of fetal liver cells



No. of mice that survived until week 4 after transplantation
No. of cells injected/mouse
CXCR4+/+
CXCR4-/-
5 × 106 5/5 5/5 
2 × 106  5/5   2/5  
106 4/5 1/5 
0.5 × 106  2/5   0/5  
0.25 × 106
 
2/5
 
0/5
 


No. of mice that survived until week 4 after transplantation
No. of cells injected/mouse
CXCR4+/+
CXCR4-/-
5 × 106 5/5 5/5 
2 × 106  5/5   2/5  
106 4/5 1/5 
0.5 × 106  2/5   0/5  
0.25 × 106
 
2/5
 
0/5
 

Freshly isolated fetal liver cells were engrafted to lethally irradiated recipient mice by limiting injection of cells as indicated. All values are expressed as “n/5,” meaning the number of mice who survived (n) when 5 mice were engrafted.

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