Effect of rapamycin on murine MK ploidization
. | Difference in ploidy, % . | n . | P . |
|---|---|---|---|
| WT | 29.8 ± 1.6 | 4 | < .001 |
| CdknIb (p27)-/- | 36 ± 7 | 3 | < .003 |
| CdknIa (p21)-/- | 14 ± 3 | 3 | < .017 |
. | Difference in ploidy, % . | n . | P . |
|---|---|---|---|
| WT | 29.8 ± 1.6 | 4 | < .001 |
| CdknIb (p27)-/- | 36 ± 7 | 3 | < .003 |
| CdknIa (p21)-/- | 14 ± 3 | 3 | < .017 |
Data represents the difference in mean ploidy of murine MKs grown with TPO alone or TPO + Rapa. Results are expressed as the mean ± SEM.