Binding of human-SIRPα and anti-CD47 to RBCs from multiple species
. | SIRPα1ex . | BRIC126 . | B6H12 . | 2D3 . | 6H9 . | CIKm1 . | mIAP301 . |
|---|---|---|---|---|---|---|---|
| Human | + | ++ | ++ | ++ | ++ | ++ | − |
| Pig | ++ | + | − | − | ++ | ++ | ND |
| Cow | −* | − | − | − | + | ++ | ND |
| Rat | − | − | − | − | − | − | ND |
| Mouse | − | ND | ND | ND | ND | ND | ++ |
. | SIRPα1ex . | BRIC126 . | B6H12 . | 2D3 . | 6H9 . | CIKm1 . | mIAP301 . |
|---|---|---|---|---|---|---|---|
| Human | + | ++ | ++ | ++ | ++ | ++ | − |
| Pig | ++ | + | − | − | ++ | ++ | ND |
| Cow | −* | − | − | − | + | ++ | ND |
| Rat | − | − | − | − | − | − | ND |
| Mouse | − | ND | ND | ND | ND | ND | ++ |
+ indicates weak, >2×BKGD (background) and <10×BKGD; ++, strong, >10×BKGD; −, very weak, <2×BKGD; and ND, not determined.
Visibly distinct but very weak.