Table 3

Planned chemotherapy regimens

DrugAdministration, method (time)Standard BEACOPP dosesEscalated BEACOPP doses
Bleomycin IV (d 8) IU/m2/d 10 IU/m2/d 
Etoposide IV (d 1-3) 100 mg/m2/d 200 mg/m2/d 
Doxorubicin IV (d 1) 25 mg/m2/d 35 mg/m2/d 
Cyclophosphamide* IV (d 1) 650 mg/m2/d 1250 mg/m2/d 
Vincristine† IV (d 8) 1.4 mg/m2/d 1.4 mg/m2/d 
Procarbazine PO (d 1-7) 100 mg/m2/d 100 mg/m2/d 
Prednisone PO (d 1-7) 40 mg/m2/d 40 mg/m2/d 
DrugAdministration, method (time)Standard BEACOPP dosesEscalated BEACOPP doses
Bleomycin IV (d 8) IU/m2/d 10 IU/m2/d 
Etoposide IV (d 1-3) 100 mg/m2/d 200 mg/m2/d 
Doxorubicin IV (d 1) 25 mg/m2/d 35 mg/m2/d 
Cyclophosphamide* IV (d 1) 650 mg/m2/d 1250 mg/m2/d 
Vincristine† IV (d 8) 1.4 mg/m2/d 1.4 mg/m2/d 
Procarbazine PO (d 1-7) 100 mg/m2/d 100 mg/m2/d 
Prednisone PO (d 1-7) 40 mg/m2/d 40 mg/m2/d 

IV indicates intravenously; PO, orally.

*

MESNA, total dose is the same as that of cyclophosphamide, administered: 20% IV at hour 0; 40% PO at hour 2; 40% PO at hour 5.

†

Vincristine, up to 2 mg (maximal dose).

Adapted from Diehl et al.2 

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