Characteristics of patients, samples, and assays used
| . | Data . |
|---|---|
| Patients | |
| No. of patients | 105 |
| Median age at diagnosis, y (range) | 28 (15-61) |
| Median duration of therapy, mo (range) | 14.4 (8.2-20.4) |
| ALL lineage | |
| Precursor B | 67 |
| Thymic T | 38 |
| Sex | |
| Female | 30 |
| Male | 75 |
| Samples | |
| Total, no. (no. after wk 52) | 519 (414) |
| Median no. samples per patient (range) | 3 (1-12) |
| Assays | |
| No. of patients investigated with only 1 molecular marker | 22 |
| No. of patients investigated with 2 molecular markers | 83 |
| Median duration of monitoring after end of first y of therapy, mo (range) | 16.1 (0.7-41.1) |
| Usage of molecular markers | |
| IgH, incomplete | 5 |
| IgH, complete | 49 |
| KDE | 21 |
| TCRβ, incomplete | 12 |
| TCRβ, complete | 41 |
| TCRγ | 29 |
| TCRδ, incomplete | 19 |
| TCRδ, complete | 12 |
| Quality of assays | |
| Sensitivities reached | |
| 1 × 10−5 | 26 |
| 5 × 10−5 | 77 |
| 1 × 10−4 | 51 |
| 5 × 10−4 | 21 |
| 1 × 10−3 | 10 |
| 1 × 10−2 | 3 |
| Quantitative ranges | |
| 1 × 10−4 | 108 |
| 5 × 10−4 | 37 |
| 1 × 10−3 | 32 |
| 1 × 10−2 | 10 |
| 1 × 10−1 | 1 |
| . | Data . |
|---|---|
| Patients | |
| No. of patients | 105 |
| Median age at diagnosis, y (range) | 28 (15-61) |
| Median duration of therapy, mo (range) | 14.4 (8.2-20.4) |
| ALL lineage | |
| Precursor B | 67 |
| Thymic T | 38 |
| Sex | |
| Female | 30 |
| Male | 75 |
| Samples | |
| Total, no. (no. after wk 52) | 519 (414) |
| Median no. samples per patient (range) | 3 (1-12) |
| Assays | |
| No. of patients investigated with only 1 molecular marker | 22 |
| No. of patients investigated with 2 molecular markers | 83 |
| Median duration of monitoring after end of first y of therapy, mo (range) | 16.1 (0.7-41.1) |
| Usage of molecular markers | |
| IgH, incomplete | 5 |
| IgH, complete | 49 |
| KDE | 21 |
| TCRβ, incomplete | 12 |
| TCRβ, complete | 41 |
| TCRγ | 29 |
| TCRδ, incomplete | 19 |
| TCRδ, complete | 12 |
| Quality of assays | |
| Sensitivities reached | |
| 1 × 10−5 | 26 |
| 5 × 10−5 | 77 |
| 1 × 10−4 | 51 |
| 5 × 10−4 | 21 |
| 1 × 10−3 | 10 |
| 1 × 10−2 | 3 |
| Quantitative ranges | |
| 1 × 10−4 | 108 |
| 5 × 10−4 | 37 |
| 1 × 10−3 | 32 |
| 1 × 10−2 | 10 |
| 1 × 10−1 | 1 |