Hematologic profile of Gimap5−/− mice
| . | Units . | gimap5−/− . | Wild-type . | N . | P . |
|---|---|---|---|---|---|
| Peripheral blood | |||||
| RBC | 106/μL | 9.0 ± 0.8 | 10.3 ± 0.1 | 15/13 | .13 |
| Hemoglobin | g × 100 mL−1 | 12.9 ± 1.2 | 15.2 ± 0.3 | 15/13 | .08 |
| Hematocrit | % | 42.2 ± 3.9 | 48.2 ± 0.4 | 15/13 | .15 |
| RBC-MCV | fL | 47.3 ± 1.1 | 46.8 ± 0.6 | 15/13 | .68 |
| RBC distribution width | % | 20.2 ± 0.8 | 14.1 ± 0.1 | 15/13 | <.005 |
| Platelets | 103/mL | 271 ± 52 | 399 ± 60 | 15/13 | .12 |
| Leukocytes | 103/μL | 7.0 ± 1.1 | 4.6 ± 0.4 | 13/12 | <.05 |
| Lymphocytes | % | 29.0 ± 3.4 | 63.8 ± 2.4 | 13/12 | <.05 |
| Lymphocytes | 103/μL | 1.8 ± 0.3 | 2.8 ± 0.2 | 13/12 | <.005 |
| Monocytes | % | 8.1 ± 0.7 | 10.8 ± 0.6 | 13/12 | <.05 |
| Monocytes | 103/μL | 0.6 ± 0.1 | 0.5 ± 0.1 | 13/12 | .61 |
| Granulocytes | % | 63.0 ± 3.9 | 25.6 ± 2.1 | 13/12 | <.005 |
| Granulocytes | 103/μL | 4.6 ± 0.8 | 1.2 ± 0.2 | 13/12 | <.005 |
| CD90.2+ | % | 8.6 ± 1.6 | 29.9 ± 2.3 | 6/6 | <.005 |
| Gr1+ | % | 55.4 ± 11.2 | 21.8 ± 2.6 | 6/6 | <.05 |
| B220+ | % | 36.0 ± 11.6 | 48.3 ± 2.3 | 6/6 | .35 |
| Spleen | |||||
| CD4+ plus CD8+ | % | 11.2 ± 1.8 | 38.2 ± 3.0 | 7/5 | <.005 |
| CD4+ | % | 10.5 ± 1.8 | 24.5 ± 2.4 | 7/5 | <.005 |
| CD8+ | % | 0.7 ± 0.1 | 13.6 ± 0.8 | 7/5 | <.005 |
| Gr1+ | % | 32.7 ± 13.1 | 4.9 ± 0.5 | 2/2 | |
| B220+ or CD19+ | % | 16.1 ± 6.3 | 49.6 ± 1.9 | 5/5 | <.005 |
| Inguinal lymph node | |||||
| CD4+ plus CD8+ | % | 30.7 ± 4.6 | 69.0 ± 1.6 | 7/5 | <.005 |
| CD4+ | % | 30.2 ± 4.5 | 44.8 ± 1.3 | 7/5 | <.05 |
| CD8+ | % | 0.5 ± 0.2 | 24.2 ± 0.7 | 7/5 | <.005 |
| Gr1+ | % | 0.9 ± 0.2 | 2.1 ± 01.2 | 5/5 | .38 |
| B220+ or CD19+ | % | 9.0 ± 2.1 | 15.6 ± 4.5 | 5/5 | .24 |
| Pancreatic lymph node | |||||
| CD4+ plus CD8+ | % | 14.8 ± 4.1 | 54.9 ± 2.7 | 3/3 | <.005 |
| CD4+ | % | 13.9 ± 3.7 | 33.3 ± 1.9 | 3/3 | <.05 |
| CD8+ | % | 0.9 ± 0.4 | 21.5 ± 0.9 | 3/3 | <.005 |
| Gr1+ | % | 10.9 ± 7.2 | 6.2 ± 0.2 | 3/3 | .58 |
| B220+ or CD19+ | % | 8.3 ± 3.4 | 29.1 ± 3.3 | 3/3 | <.05 |
| . | Units . | gimap5−/− . | Wild-type . | N . | P . |
|---|---|---|---|---|---|
| Peripheral blood | |||||
| RBC | 106/μL | 9.0 ± 0.8 | 10.3 ± 0.1 | 15/13 | .13 |
| Hemoglobin | g × 100 mL−1 | 12.9 ± 1.2 | 15.2 ± 0.3 | 15/13 | .08 |
| Hematocrit | % | 42.2 ± 3.9 | 48.2 ± 0.4 | 15/13 | .15 |
| RBC-MCV | fL | 47.3 ± 1.1 | 46.8 ± 0.6 | 15/13 | .68 |
| RBC distribution width | % | 20.2 ± 0.8 | 14.1 ± 0.1 | 15/13 | <.005 |
| Platelets | 103/mL | 271 ± 52 | 399 ± 60 | 15/13 | .12 |
| Leukocytes | 103/μL | 7.0 ± 1.1 | 4.6 ± 0.4 | 13/12 | <.05 |
| Lymphocytes | % | 29.0 ± 3.4 | 63.8 ± 2.4 | 13/12 | <.05 |
| Lymphocytes | 103/μL | 1.8 ± 0.3 | 2.8 ± 0.2 | 13/12 | <.005 |
| Monocytes | % | 8.1 ± 0.7 | 10.8 ± 0.6 | 13/12 | <.05 |
| Monocytes | 103/μL | 0.6 ± 0.1 | 0.5 ± 0.1 | 13/12 | .61 |
| Granulocytes | % | 63.0 ± 3.9 | 25.6 ± 2.1 | 13/12 | <.005 |
| Granulocytes | 103/μL | 4.6 ± 0.8 | 1.2 ± 0.2 | 13/12 | <.005 |
| CD90.2+ | % | 8.6 ± 1.6 | 29.9 ± 2.3 | 6/6 | <.005 |
| Gr1+ | % | 55.4 ± 11.2 | 21.8 ± 2.6 | 6/6 | <.05 |
| B220+ | % | 36.0 ± 11.6 | 48.3 ± 2.3 | 6/6 | .35 |
| Spleen | |||||
| CD4+ plus CD8+ | % | 11.2 ± 1.8 | 38.2 ± 3.0 | 7/5 | <.005 |
| CD4+ | % | 10.5 ± 1.8 | 24.5 ± 2.4 | 7/5 | <.005 |
| CD8+ | % | 0.7 ± 0.1 | 13.6 ± 0.8 | 7/5 | <.005 |
| Gr1+ | % | 32.7 ± 13.1 | 4.9 ± 0.5 | 2/2 | |
| B220+ or CD19+ | % | 16.1 ± 6.3 | 49.6 ± 1.9 | 5/5 | <.005 |
| Inguinal lymph node | |||||
| CD4+ plus CD8+ | % | 30.7 ± 4.6 | 69.0 ± 1.6 | 7/5 | <.005 |
| CD4+ | % | 30.2 ± 4.5 | 44.8 ± 1.3 | 7/5 | <.05 |
| CD8+ | % | 0.5 ± 0.2 | 24.2 ± 0.7 | 7/5 | <.005 |
| Gr1+ | % | 0.9 ± 0.2 | 2.1 ± 01.2 | 5/5 | .38 |
| B220+ or CD19+ | % | 9.0 ± 2.1 | 15.6 ± 4.5 | 5/5 | .24 |
| Pancreatic lymph node | |||||
| CD4+ plus CD8+ | % | 14.8 ± 4.1 | 54.9 ± 2.7 | 3/3 | <.005 |
| CD4+ | % | 13.9 ± 3.7 | 33.3 ± 1.9 | 3/3 | <.05 |
| CD8+ | % | 0.9 ± 0.4 | 21.5 ± 0.9 | 3/3 | <.005 |
| Gr1+ | % | 10.9 ± 7.2 | 6.2 ± 0.2 | 3/3 | .58 |
| B220+ or CD19+ | % | 8.3 ± 3.4 | 29.1 ± 3.3 | 3/3 | <.05 |