Percentage of clonogenicity
| Name . | Clonogenicity, % . | Reduction, % . | |
|---|---|---|---|
| Dox− . | Dox + . | ||
| A1 | 17.80 | 8.70 | 51 |
| A2 | 24.40 | 12.32 | 50 |
| A2B | 18.30 | 9.70 | 47 |
| A2C | 10.80 | 4.80 | 56 |
| C | 19.10 | 18.20 | 5 |
| Name . | Clonogenicity, % . | Reduction, % . | |
|---|---|---|---|
| Dox− . | Dox + . | ||
| A1 | 17.80 | 8.70 | 51 |
| A2 | 24.40 | 12.32 | 50 |
| A2B | 18.30 | 9.70 | 47 |
| A2C | 10.80 | 4.80 | 56 |
| C | 19.10 | 18.20 | 5 |
The percentage of clonogenicity (colony number at day 6/number of seeded cells) was determined in methylcellulose assay with 500 cells seeded in 1 mL medium in the presence of 500 ng/mL dox (Dox+) or without (Dox−). Colonies containing a minimum of 50 cells were scored. The percentage of clonogenicity in the treated and the untreated respective cells were statistically different (P < .05) as calculated by the Student t test. The percentage of reduction is calculated relative to untreated cells. Results are the mean of 6 independent experiments.