Comparison of response to AZT and IFN-α by c-Rel and by IRF-4 expression
| Response . | c-Rel− (%) . | c-Rel+ (%) . | P . | IRF-4− (%) . | IRF4+ (%) . | P . |
|---|---|---|---|---|---|---|
| CR | 5 (41.7) | 0 (0.0) | .106 | 5 (55.6) | 0 (0.0) | .008 |
| PR | 3 (0.25) | 1 (14.3) | — | 2 (22.2) | 1 (9.1) | — |
| CR + PR | 8 (66.7) | 1 (14.3) | .057 | 7 (77.8) | 1 (9.1) | .005 |
| NR | 4 (0.33) | 6 (85.7) | — | 2 (22.2) | 10 (90.9) | — |
| Total | 12 (100) | 7 (100) | — | 9 (100) | 11 (100) | — |
| Response . | c-Rel− (%) . | c-Rel+ (%) . | P . | IRF-4− (%) . | IRF4+ (%) . | P . |
|---|---|---|---|---|---|---|
| CR | 5 (41.7) | 0 (0.0) | .106 | 5 (55.6) | 0 (0.0) | .008 |
| PR | 3 (0.25) | 1 (14.3) | — | 2 (22.2) | 1 (9.1) | — |
| CR + PR | 8 (66.7) | 1 (14.3) | .057 | 7 (77.8) | 1 (9.1) | .005 |
| NR | 4 (0.33) | 6 (85.7) | — | 2 (22.2) | 10 (90.9) | — |
| Total | 12 (100) | 7 (100) | — | 9 (100) | 11 (100) | — |
P values were determined by 2-sided Fisher exact test. Whole numbers = number of patients.
CR indicates complete response; PR, partial response; NR, no response; —, not determined.