Table 3. Type and frequency of adverse... | American Society of Hematology

Table 3.

Type and frequency of adverse events

	Treatment group*
Adverse event	Placebo	0.025 mg/kg	0.05 mg/kg	0.1 mg/kg
No. subjects	8	5	5	10
Cardiac disorder: palpitations	0	1 (20.0)	0	0
Gastrointestinal disorders
Abdominal distention	0	1 (20.0)	0	0
Abdominal pain	0	1 (20.0)	0	1 (10.0)
Constipation	0	1 (20.0)	0	0
Diarrhea	0	1 (20.0)	0	0
Nausea	0	0	0	2 (20.0)
General disorders
Fatigue	0	1 (20.0)	0	0
Thirst	0	0	0	1 (10.0)
Immune system disorder: drug hypersensitivity	0	1 (20.0)	0	0
Infection: nasopharyngitis	3 (37.5)	0	0	2 (20.0)
Injury
Head injury	0	0	0	1 (10.0)
Joint sprain	0	0	0	1 (10.0)
Limb injury	1 (12.5)	0	0	0
Musculoskeletal disorder: back pain	0	0	0	1 (10.0)
Nervous system disorders
Dizziness	0	0	0	1 (10.0)
Headache	1 (12.5)	1 (20.0)	0	3 (30.0)
Syncope vasovagal	1 (12.5)	0	0	0
Reproductive system disorder:
testicular disorder	0	0	0	1 (10.0)

	Treatment group*
Adverse event	Placebo	0.025 mg/kg	0.05 mg/kg	0.1 mg/kg
No. subjects	8	5	5	10
Cardiac disorder: palpitations	0	1 (20.0)	0	0
Gastrointestinal disorders
Abdominal distention	0	1 (20.0)	0	0
Abdominal pain	0	1 (20.0)	0	1 (10.0)
Constipation	0	1 (20.0)	0	0
Diarrhea	0	1 (20.0)	0	0
Nausea	0	0	0	2 (20.0)
General disorders
Fatigue	0	1 (20.0)	0	0
Thirst	0	0	0	1 (10.0)
Immune system disorder: drug hypersensitivity	0	1 (20.0)	0	0
Infection: nasopharyngitis	3 (37.5)	0	0	2 (20.0)
Injury
Head injury	0	0	0	1 (10.0)
Joint sprain	0	0	0	1 (10.0)
Limb injury	1 (12.5)	0	0	0
Musculoskeletal disorder: back pain	0	0	0	1 (10.0)
Nervous system disorders
Dizziness	0	0	0	1 (10.0)
Headache	1 (12.5)	1 (20.0)	0	3 (30.0)
Syncope vasovagal	1 (12.5)	0	0	0
Reproductive system disorder:
testicular disorder	0	0	0	1 (10.0)

Except for the “No. patients” row, all data are presented as number of subjects experiencing adverse event (%).