Crude and predicted bone age by inhibitor status among HIV− adolescents
| Chronological age, y . | Crude bone age . | Predicted bone age . | 95% CI, mo . | P . | |||
|---|---|---|---|---|---|---|---|
| Without inhibitor, y ± SE . | With inhibitor, y ± SE . | Without inhibitor, y . | With inhibitor, y . | Difference, mo . | |||
| 11 | 10.5 ± 0.3 | 9.8 ± 0.4 | 10.7 | 10.0 | 8.7 | 2.3, 15.1 | .008 |
| 12 | 12.2 ± 0.2 | 11.3 ± 0.4 | 12.0 | 11.2 | 9.5 | 3.0, 16.1 | .005 |
| 13 | 13.0 ± 0.3 | 11.7 ± 0.5 | 13.2 | 12.4 | 9.9 | 3.2, 16.6 | .004 |
| 14 | 14.3 ± 0.3 | 14.7 ± 0.6 | 14.4 | 13.6 | 9.8 | 2.9, 16.7 | .005 |
| 15 | 15.8 ± 0.3 | 14.8 ± 0.3 | 15.5 | 14.8 | 9.2 | 2.2, 16.2 | .01 |
| Chronological age, y . | Crude bone age . | Predicted bone age . | 95% CI, mo . | P . | |||
|---|---|---|---|---|---|---|---|
| Without inhibitor, y ± SE . | With inhibitor, y ± SE . | Without inhibitor, y . | With inhibitor, y . | Difference, mo . | |||
| 11 | 10.5 ± 0.3 | 9.8 ± 0.4 | 10.7 | 10.0 | 8.7 | 2.3, 15.1 | .008 |
| 12 | 12.2 ± 0.2 | 11.3 ± 0.4 | 12.0 | 11.2 | 9.5 | 3.0, 16.1 | .005 |
| 13 | 13.0 ± 0.3 | 11.7 ± 0.5 | 13.2 | 12.4 | 9.9 | 3.2, 16.6 | .004 |
| 14 | 14.3 ± 0.3 | 14.7 ± 0.6 | 14.4 | 13.6 | 9.8 | 2.9, 16.7 | .005 |
| 15 | 15.8 ± 0.3 | 14.8 ± 0.3 | 15.5 | 14.8 | 9.2 | 2.2, 16.2 | .01 |
A total of 319 films from 120 HIV− participants were used in the analysis to estimate the predicted bone ages; 10 films from 6 participants were excluded from the analysis because they were skeletally mature at baseline.