Table 1 T-dependent immune responses to... | American Society of Hematology

Table 1

T-dependent immune responses to NP-CGG in control and CD19-Cre-DNMAML1 mice

	No. of mice	NP⁺ cells: % live / Abs no.	Germinal center cells: % NP⁺ / Abs no. / % GFP⁺	Plasma cells: % NP⁺ / Abs no. / % GFP⁺	IgG1⁺B220⁺ cells: % NP⁺ / Abs no. / % GFP⁺	IgG1⁺B220⁻ cells: % NP⁺ / Abs no. / % GFP⁺
Control	7	0.94 ± 0.2 / 96 ± 17	50 ± 5 / 51 ± 12 / NA	24 ± 3 / 23 ± 5 / NA	19 ± 2 / 20 ± 5 / NA	23 ± 1 / 22 ± 4 / NA
CD19-Cre-DNMAML1	9	0.79 ± 0.1 / 73 ± 13	81 ± 5* / 57 ± 10 / 86 ± 2	14 ± 2† / 11 ± 3 / 68 ± 4	22 ± 1 / 16 ± 3 / 88 ± 2	10 ± 1* / 8 ± 2†/ 69 ± 5

	No. of mice	NP⁺ cells: % live / Abs no.	Germinal center cells: % NP⁺ / Abs no. / % GFP⁺	Plasma cells: % NP⁺ / Abs no. / % GFP⁺	IgG1⁺B220⁺ cells: % NP⁺ / Abs no. / % GFP⁺	IgG1⁺B220⁻ cells: % NP⁺ / Abs no. / % GFP⁺
Control	7	0.94 ± 0.2 / 96 ± 17	50 ± 5 / 51 ± 12 / NA	24 ± 3 / 23 ± 5 / NA	19 ± 2 / 20 ± 5 / NA	23 ± 1 / 22 ± 4 / NA
CD19-Cre-DNMAML1	9	0.79 ± 0.1 / 73 ± 13	81 ± 5* / 57 ± 10 / 86 ± 2	14 ± 2† / 11 ± 3 / 68 ± 4	22 ± 1 / 16 ± 3 / 88 ± 2	10 ± 1* / 8 ± 2†/ 69 ± 5

B-cell populations defined by flow cytometry as shown in Figures 7 and S3. Frequencies indicate percentage of live cells or percentage of NP⁺ cells; absolute numbers (Abs no.), × 10⁵. Results represent combined data from 4 independent experiments.

P < .001.

†

P < .02.

View Large

This Feature Is Available To Subscribers Only