Combination therapy for refractory ITP: doses of intravenous and oral agents
| Agent . | Dose . |
|---|---|
| Acute (IV) | |
| Methylprednisolone | 30 mg/kg; max 1 g |
| IVIG | 1 g/kg |
| Anti-D | 75 μg/kg |
| Vincristine | 0.03 mg/kg; max 1.5 mg |
| Vinblastine | 10 mg (∼ 0.2 mg/kg) |
| Maintenance (po) | |
| Danazol | 10 mg/kg; round to the nearest 200 mg; 400-800 mg/day in adults |
| Azathioprine | 2-2.5 mg/ kg; round to the nearest 50 mg; 100-200 mg/day in adults |
| Agent . | Dose . |
|---|---|
| Acute (IV) | |
| Methylprednisolone | 30 mg/kg; max 1 g |
| IVIG | 1 g/kg |
| Anti-D | 75 μg/kg |
| Vincristine | 0.03 mg/kg; max 1.5 mg |
| Vinblastine | 10 mg (∼ 0.2 mg/kg) |
| Maintenance (po) | |
| Danazol | 10 mg/kg; round to the nearest 200 mg; 400-800 mg/day in adults |
| Azathioprine | 2-2.5 mg/ kg; round to the nearest 50 mg; 100-200 mg/day in adults |