Seventeen patients received multiple courses of acute intravenous combination therapy
| Patient . | Responses/no. of acute IV combination treatments . | First . | Second . | Third . | Fourth . | Fifth . | Sixth . | Seventh . | Eighth . |
|---|---|---|---|---|---|---|---|---|---|
| A | 7/7 | R | R | R | R | R | R | R | |
| B | 8/8 | R | R | R | R | R | R | R | R |
| C | 3/3 | R | R | R | — | — | — | — | — |
| D | 2/2 | R | R | — | — | — | — | — | — |
| E | 5/5 | R | R | R | R | R | — | — | — |
| F | 5/5 | R | R | R | R | R | — | — | — |
| G | 2/2 | R | R | — | — | — | |||
| H | 4/6 | R | NR 10 | R | NR 22 | R | R | — | — |
| I | 0/4 | NR 24 | NR 15 | NR 16 | NR 5 | — | — | — | — |
| J | 1/2 | NR 6 | R | — | — | — | — | — | — |
| K | 3/3 | R | R | R | — | — | — | — | — |
| L | 0/2 | NR 40 | NR 24 | — | — | — | — | — | — |
| M | 4/6 | R | R | R | NR 37 | NR 9 | R | — | — |
| N | 2/5 | NR 3 | NR 4 | R | R | NR 20 | — | — | — |
| O | 3/3 | R | R | R | — | — | — | — | — |
| P | 4/5 | R | NR 8 | R | R | R | — | — | — |
| Q | 5/6 | NR 5 | R | R | R | R | R | — | — |
| Patient . | Responses/no. of acute IV combination treatments . | First . | Second . | Third . | Fourth . | Fifth . | Sixth . | Seventh . | Eighth . |
|---|---|---|---|---|---|---|---|---|---|
| A | 7/7 | R | R | R | R | R | R | R | |
| B | 8/8 | R | R | R | R | R | R | R | R |
| C | 3/3 | R | R | R | — | — | — | — | — |
| D | 2/2 | R | R | — | — | — | — | — | — |
| E | 5/5 | R | R | R | R | R | — | — | — |
| F | 5/5 | R | R | R | R | R | — | — | — |
| G | 2/2 | R | R | — | — | — | |||
| H | 4/6 | R | NR 10 | R | NR 22 | R | R | — | — |
| I | 0/4 | NR 24 | NR 15 | NR 16 | NR 5 | — | — | — | — |
| J | 1/2 | NR 6 | R | — | — | — | — | — | — |
| K | 3/3 | R | R | R | — | — | — | — | — |
| L | 0/2 | NR 40 | NR 24 | — | — | — | — | — | — |
| M | 4/6 | R | R | R | NR 37 | NR 9 | R | — | — |
| N | 2/5 | NR 3 | NR 4 | R | R | NR 20 | — | — | — |
| O | 3/3 | R | R | R | — | — | — | — | — |
| P | 4/5 | R | NR 8 | R | R | R | — | — | — |
| Q | 5/6 | NR 5 | R | R | R | R | R | — | — |
The number of responses per number of acute intravenous combination treatments given is indicated for 12 adults (A-L) and 5 children (M-Q). The peak platelet count (×109/L) for the treatments to which there was no response is shown. There were 58 responses (78%) to 74 treatments given.
— indicates not applicable; R, response; and NR, nonresponse.