Incorporation of lymphoid neoplasm subtypes defined by the Working Formulation into the proposed WHO-based nested classification of malignant lymphoid neoplasms, without immunophenotype data
| Working Formulation categories . | Hierarchical group . | |||||
|---|---|---|---|---|---|---|
| 1 . | 2 . | 3 . | 4 . | 5 . | 6 . | |
| A. Small lymphocytic | LN | NHL | B-NHL | Mature B-NHL | — | — |
| B. Follicular, small cleaved cell | LN | NHL | B-NHL | Mature B-NHL | FL | — |
| C. Follicular, mixed small cleaved and large cell | LN | NHL | B-NHL | Mature B-NHL | FL | — |
| D. Follicular, large cell | LN | NHL | B-NHL | Mature B-NHL | FL | — |
| E. Diffuse, small cleaved cell | LN | NHL | B-NHL | Mature B-NHL | — | — |
| F. Diffuse, mixed small and large cell | LN | NHL | — | — | — | — |
| G. Diffuse, large cell | LN | NHL | B-NHL | Mature B-NHL | DLBCL | — |
| H. Large cell, immunoblastic | LN | NHL | — | — | — | — |
| I. Lymphoblastic | LN | NHL | — | Precursor | — | — |
| J. Small noncleaved cell | LN | NHL | B-NHL | Mature B-NHL | — | — |
| K. Unclassified | LN | NHL | — | — | — | — |
| Working Formulation categories . | Hierarchical group . | |||||
|---|---|---|---|---|---|---|
| 1 . | 2 . | 3 . | 4 . | 5 . | 6 . | |
| A. Small lymphocytic | LN | NHL | B-NHL | Mature B-NHL | — | — |
| B. Follicular, small cleaved cell | LN | NHL | B-NHL | Mature B-NHL | FL | — |
| C. Follicular, mixed small cleaved and large cell | LN | NHL | B-NHL | Mature B-NHL | FL | — |
| D. Follicular, large cell | LN | NHL | B-NHL | Mature B-NHL | FL | — |
| E. Diffuse, small cleaved cell | LN | NHL | B-NHL | Mature B-NHL | — | — |
| F. Diffuse, mixed small and large cell | LN | NHL | — | — | — | — |
| G. Diffuse, large cell | LN | NHL | B-NHL | Mature B-NHL | DLBCL | — |
| H. Large cell, immunoblastic | LN | NHL | — | — | — | — |
| I. Lymphoblastic | LN | NHL | — | Precursor | — | — |
| J. Small noncleaved cell | LN | NHL | B-NHL | Mature B-NHL | — | — |
| K. Unclassified | LN | NHL | — | — | — | — |
Without immunophenotype data, this translation is appropriate for predominantly white populations only. Abbreviations are explained in Table 1.
— indicates category cannot be assigned.