Table 1

Distribution of odds ratio, P values, and 95% confidence intervals according to putative risk factors for case patients and controls

Risk factorsCase patients
Controls
OR overallP valueOR§ idiopathic95% CI§
YesNoYesNo
Male 219 296 224 331     
Diabetes 131 384 85 470 2.1 < 0.001 2.6 1.7-3.8 
Hypertension 256 259 258 297 1.3 0.09 1.3 0.95-1.9 
Cigarette smoking 232 283 217 338 1.3 0.02 1.3 0.97-1.9 
Obesity 211 302 255 300 0.83 0.13 1.2 0.90-1.7 
Exercise 225 290 320 235 0.56 < 0.001 0.63 0.46-0.86 
Family history of venous thromboembolism 90 321 49 465 2.7 < 0.001 3.2 2.1-5.1 
Factor V Leiden 509 554 6.6 0.08 4.4 0.39-48.2 
Prothrombin mutation 511 555  0.05  0.96 
Risk factorsCase patients
Controls
OR overallP valueOR§ idiopathic95% CI§
YesNoYesNo
Male 219 296 224 331     
Diabetes 131 384 85 470 2.1 < 0.001 2.6 1.7-3.8 
Hypertension 256 259 258 297 1.3 0.09 1.3 0.95-1.9 
Cigarette smoking 232 283 217 338 1.3 0.02 1.3 0.97-1.9 
Obesity 211 302 255 300 0.83 0.13 1.2 0.90-1.7 
Exercise 225 290 320 235 0.56 < 0.001 0.63 0.46-0.86 
Family history of venous thromboembolism 90 321 49 465 2.7 < 0.001 3.2 2.1-5.1 
Factor V Leiden 509 554 6.6 0.08 4.4 0.39-48.2 
Prothrombin mutation 511 555  0.05  0.96 

CI indicates confidence interval.

Risk factors are self-reported except for the factor V Leiden and prothrombin mutation.

Odds ratio (OR) and P values are adjusted for age and sex.

§

Odds ratio pertains to 229 idiopathic cases and all controls with adjustment for age and sex.

Matching factor.

Unadjusted (crude) results with exact mid P value or lower confidence limit.

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