Distribution of odds ratio, P values, and 95% confidence intervals according to putative risk factors † for case patients and controls
Risk factors . | Case patients . | Controls . | OR‡ overall . | P value‡ . | OR§ idiopathic . | 95% CI§ . | ||
---|---|---|---|---|---|---|---|---|
Yes . | No . | Yes . | No . | |||||
Male | 219 | 296 | 224 | 331 | ¶ | ¶ | ¶ | ¶ |
Diabetes | 131 | 384 | 85 | 470 | 2.1 | < 0.001 | 2.6 | 1.7-3.8 |
Hypertension | 256 | 259 | 258 | 297 | 1.3 | 0.09 | 1.3 | 0.95-1.9 |
Cigarette smoking | 232 | 283 | 217 | 338 | 1.3 | 0.02 | 1.3 | 0.97-1.9 |
Obesity | 211 | 302 | 255 | 300 | 0.83 | 0.13 | 1.2 | 0.90-1.7 |
Exercise | 225 | 290 | 320 | 235 | 0.56 | < 0.001 | 0.63 | 0.46-0.86 |
Family history of venous thromboembolism | 90 | 321 | 49 | 465 | 2.7 | < 0.001 | 3.2 | 2.1-5.1 |
Factor V Leiden | 6 | 509 | 1 | 554 | 6.6 | 0.08 | 4.4 | 0.39-48.2 |
Prothrombin mutation | 4 | 511 | 0 | 555 | ∞‖ | 0.05‖ | ∞‖ | 0.96‖ |
Risk factors . | Case patients . | Controls . | OR‡ overall . | P value‡ . | OR§ idiopathic . | 95% CI§ . | ||
---|---|---|---|---|---|---|---|---|
Yes . | No . | Yes . | No . | |||||
Male | 219 | 296 | 224 | 331 | ¶ | ¶ | ¶ | ¶ |
Diabetes | 131 | 384 | 85 | 470 | 2.1 | < 0.001 | 2.6 | 1.7-3.8 |
Hypertension | 256 | 259 | 258 | 297 | 1.3 | 0.09 | 1.3 | 0.95-1.9 |
Cigarette smoking | 232 | 283 | 217 | 338 | 1.3 | 0.02 | 1.3 | 0.97-1.9 |
Obesity | 211 | 302 | 255 | 300 | 0.83 | 0.13 | 1.2 | 0.90-1.7 |
Exercise | 225 | 290 | 320 | 235 | 0.56 | < 0.001 | 0.63 | 0.46-0.86 |
Family history of venous thromboembolism | 90 | 321 | 49 | 465 | 2.7 | < 0.001 | 3.2 | 2.1-5.1 |
Factor V Leiden | 6 | 509 | 1 | 554 | 6.6 | 0.08 | 4.4 | 0.39-48.2 |
Prothrombin mutation | 4 | 511 | 0 | 555 | ∞‖ | 0.05‖ | ∞‖ | 0.96‖ |
CI indicates confidence interval.
Risk factors are self-reported except for the factor V Leiden and prothrombin mutation.
Odds ratio (OR) and P values are adjusted for age and sex.
Odds ratio pertains to 229 idiopathic cases and all controls with adjustment for age and sex.
Matching factor.
Unadjusted (crude) results with exact mid P value or lower confidence limit.