Analysis of NHL cell lines for sensitivity to rhApo2L/TRAIL alone and in combination with rituximab
| Cell lines . | NHL type . | IC50, ng/mL . | |
|---|---|---|---|
| rhApo2L/TRAIL . | rhApo2L/TRAIL + rituximab . | ||
| BJAB | BL | 32 | 26 |
| Ramos RA1 | BL | 38 | 17 |
| DoHH-2 | FL | 14 | —* |
| SC-1 | FL | > 1000 | > 1000 |
| Ramos T1 | BL | 33 | 13 |
| Raji | BL | > 1000 | > 1000 |
| Daudi | BL | > 1000 | > 1000 |
| OCI-Ly19 | DLBCL | > 1000 | > 1000 |
| Cell lines . | NHL type . | IC50, ng/mL . | |
|---|---|---|---|
| rhApo2L/TRAIL . | rhApo2L/TRAIL + rituximab . | ||
| BJAB | BL | 32 | 26 |
| Ramos RA1 | BL | 38 | 17 |
| DoHH-2 | FL | 14 | —* |
| SC-1 | FL | > 1000 | > 1000 |
| Ramos T1 | BL | 33 | 13 |
| Raji | BL | > 1000 | > 1000 |
| Daudi | BL | > 1000 | > 1000 |
| OCI-Ly19 | DLBCL | > 1000 | > 1000 |
BL indicates Burkitt lymphoma.
Rituximab (1000 ng/mL) has single-agent activity, which precludes comparing the IC50 values of the cell viability curves for this cell line.