Age-specific mortality rates from all causes in males in the United Kingdom with hemophilia A or B who were not infected with HIV
| . | Severe hemophilia, 1977-1999* . | Moderate/mild hemophilia, 1985-1999* . | All males in the United Kingdom, 1999 . | ||||
|---|---|---|---|---|---|---|---|
| No. of deaths . | Death rate per 1000 y . | 95% CI . | No. of deaths . | Death rate per 1000 y . | 95% CI . | Death rate per 1000 y . | |
| Age, y | |||||||
| 0-4 | 13 | 5.1 | 3.0-8.8 | 6 | 2.0 | 0.9-4.6 | 1.5 |
| 5-14 | 4 | 0.7 | 0.2-1.7 | 4 | 0.5 | 0.2-1.3 | 0.1 |
| 15-24 | 15 | 2.6 | 1.6-4.4 | 9 | 1.1 | 0.6-2.0 | 0.7 |
| 25-34 | 28 | 5.8 | 4.0-8.4 | 16 | 1.7 | 1.1-2.8 | 1.0 |
| 35-44 | 28 | 8.0 | 5.6-11.7 | 16 | 2.0 | 1.2-3.3 | 1.6 |
| 45-54 | 41 | 17.8 | 13.1-24.1 | 35 | 5.8 | 4.2-8.1 | 4.1 |
| 55-64 | 51 | 39.2 | 29.8-51.5 | 71 | 15.4 | 12.2-19.5 | 11.2 |
| 65-74 | 41 | 66.7 | 49.1-90.5 | 135 | 43.0 | 36.3-50.9 | 32.3 |
| 75-84 | 25 | 133.0 | 89.9-196.8 | 122 | 91.7 | 76.8-109.5 | 81.1 |
| Total deaths | 246 | — | — | 414 | — | — | — |
| . | Severe hemophilia, 1977-1999* . | Moderate/mild hemophilia, 1985-1999* . | All males in the United Kingdom, 1999 . | ||||
|---|---|---|---|---|---|---|---|
| No. of deaths . | Death rate per 1000 y . | 95% CI . | No. of deaths . | Death rate per 1000 y . | 95% CI . | Death rate per 1000 y . | |
| Age, y | |||||||
| 0-4 | 13 | 5.1 | 3.0-8.8 | 6 | 2.0 | 0.9-4.6 | 1.5 |
| 5-14 | 4 | 0.7 | 0.2-1.7 | 4 | 0.5 | 0.2-1.3 | 0.1 |
| 15-24 | 15 | 2.6 | 1.6-4.4 | 9 | 1.1 | 0.6-2.0 | 0.7 |
| 25-34 | 28 | 5.8 | 4.0-8.4 | 16 | 1.7 | 1.1-2.8 | 1.0 |
| 35-44 | 28 | 8.0 | 5.6-11.7 | 16 | 2.0 | 1.2-3.3 | 1.6 |
| 45-54 | 41 | 17.8 | 13.1-24.1 | 35 | 5.8 | 4.2-8.1 | 4.1 |
| 55-64 | 51 | 39.2 | 29.8-51.5 | 71 | 15.4 | 12.2-19.5 | 11.2 |
| 65-74 | 41 | 66.7 | 49.1-90.5 | 135 | 43.0 | 36.3-50.9 | 32.3 |
| 75-84 | 25 | 133.0 | 89.9-196.8 | 122 | 91.7 | 76.8-109.5 | 81.1 |
| Total deaths | 246 | — | — | 414 | — | — | — |
HIV-positive patients were excluded from 1985 or date of seroconversion, if later.
—indicates not applicable.
Results are shown for these calendar periods as all-cause mortality did not change significantly during 1977-1999 in severe hemophilia or during 1985-1999 in moderate/mild hemophilia (Table 2).