Table 3

Multivariate analysis of baseline parameters associated with event-free and overall survival

Variablen/N (%)HR (95% CI)P
Overall survival    
    Baseline SFLC higher than 75 mg/dL, top tertile 100/300 (33) 2.43 (1.18-5.01) .016 
    LDH of 190 U/L or higher 79/300 (26) 2.59 (1.27-5.28) .009 
    CAs 98/300 (33) 2.43 (1.21-4.89) .013 
Event-free survival    
    Baseline SFLC higher than 75 mg/dL, top tertile 100/300 (33) 2.40 (1.26-4.57) .008 
    LDH of 190 U/L or higher 79/300 (26) 2.10 (1.11-3.99) .023 
    CAs 98/300 (33) 2.21 (1.19-4.13) .012 
Variablen/N (%)HR (95% CI)P
Overall survival    
    Baseline SFLC higher than 75 mg/dL, top tertile 100/300 (33) 2.43 (1.18-5.01) .016 
    LDH of 190 U/L or higher 79/300 (26) 2.59 (1.27-5.28) .009 
    CAs 98/300 (33) 2.43 (1.21-4.89) .013 
Event-free survival    
    Baseline SFLC higher than 75 mg/dL, top tertile 100/300 (33) 2.40 (1.26-4.57) .008 
    LDH of 190 U/L or higher 79/300 (26) 2.10 (1.11-3.99) .023 
    CAs 98/300 (33) 2.21 (1.19-4.13) .012 

P value from Wald chi-square test in Cox regression analysis; multivariate model uses stepwise selection with entry level of P ≤ .1; variable remains in case of P ≤ .05.

HR indicates hazard ratio; 95% CI, 95% confidence interval.

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